Effect of the CYP2D6 genotype on the pharmacokinetics of tropisetron in healthy Korean subjects. (Q44427695)

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3 November 2019

title

Effect of the CYP2D6 genotype on the pharmacokinetics of tropisetron in healthy Korean subjects (English)

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3 November 2019

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6

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2

Joo-Youn Cho

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author name string

Myo-Kyoung Kim

1

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Hyeong-Seok Lim

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Kyoung-Seop Hong

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Jae-Yong Chung

5

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Dal-Seok Oh

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Sang-Goo Shin

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Sang-Hun Lee

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Dong-Ho Lee

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Bumchan Min

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In-Jin Jang

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language of work or name

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1 May 2003

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European Journal of Clinical Pharmacology

3 November 2019

published in

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volume

59

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page(s)

111-116

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issue

2

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https://scigraph.springernature.com/pub.10.1007/s00228-003-0595-1

3 November 2019

exact match

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Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes

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Tropisetron. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential as an antiemetic

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Risperidone metabolism in relation to CYP2D6*10 allele in Korean schizophrenic patients

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Metoprolol oxidation polymorphism in a Korean population: comparison with native Japanese and Chinese populations

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Safety, tolerability, efficacy and plasma concentrations of tropisetron after administration at five dose levels to children receiving cancer chemotherapy

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12 December 2020

Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations

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Debrisoquine and S-mephenytoin hydroxylation phenotypes and genotypes in a Korean population

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Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes

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Pharmacokinetics of therapeutic doses of tropisetron in healthy volunteers

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Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.

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Influence of the defective metabolism of sparteine on its pharmacokinetics

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Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine

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Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data

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12 December 2020

Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese

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12 December 2020

CYP2D6 genotypes in a Japanese population: low frequencies of CYP2D6 gene duplication but high frequency of CYP2D6*10

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12 December 2020

The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondansetron

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12 December 2020

Relationship of paroxetine disposition to metoprolol metabolic ratio and CYP2D6*10 genotype of Korean subjects

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12 December 2020

Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis

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12 December 2020

Correctness of prediction of the CYP2D6 phenotype confirmed by genotyping 47 intermediate and poor metabolizers of debrisoquine.

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12 December 2020

10.1007/S00228-003-0595-1

Identifiers

DOI

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3 November 2019

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