NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection. (Q44413763)

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scientific article published in May 2003

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English	NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection.	scientific article published in May 2003

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2 November 2019

NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection (English)

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2 November 2019

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2 November 2019

Mark H. Tuszynski

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Mark H Tuszynski

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2 November 2019

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Ray Grill

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Leonard L Jones

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Adam Brant

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Paul Lu

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1 May 2003

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Experimental Neurology

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47-56

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2 November 2019

Characterization and topography of high-affinity 125I-neurotrophin-3 binding to mammalian brain.

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Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

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Chronically injured supraspinal neurons exhibit only modest axonal dieback in response to a cervical hemisection lesion

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Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons.

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7 January 2021

Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery

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Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons.

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Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors.

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Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

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Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury

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Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord

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Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury

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A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.

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Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function

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based on heuristic

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Elevated gene expression in the red nucleus after spinal cord compression injury

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7 January 2021

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10.1016/S0014-4886(02)00055-9

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Europe PubMed Central

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2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12710933%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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