Discovery of the first antibacterial small molecule inhibitors of MurB. (Q44345485)

2 December 2017

Discovery of the first antibacterial small molecule inhibitors of MurB. (English)

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2 December 2017

Joanne J Bronson

1

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2 December 2017

Kenneth L DenBleyker

2

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2 December 2017

Paul J Falk

3

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2 December 2017

Robert A Mate

4

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2 December 2017

Hsu-Tso Ho

5

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2 December 2017

Michael J Pucci

6

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2 December 2017

Lawrence B Snyder

7

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2 December 2017

language of work or name

English

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publication date

1 March 2003

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Bioorganic & Medicinal Chemistry Letters

2 December 2017

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2 December 2017

13

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2 December 2017

5

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2 December 2017

873-875

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Survey of susceptibilities of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolates to 26 antimicrobial agents: a prospective U.S. study

2 December 2017

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https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: enzymology, antibiotics, and antibiotic resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Crystallization and preliminary X-ray analysis of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus

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https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

The Bacillus subtilis cell-division 135-137 degrees region contains an essential orf with significant similarity to murB and a dispensable sbp gene.

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https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

An enzyme-substrate complex involved in bacterial cell wall biosynthesis

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https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Steady-state kinetic mechanism of Escherichia coli UDP-N-acetylenolpyruvylglucosamine reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Overexpression, purification, and mechanistic study of UDP-N-acetylenolpyruvylglucosamine reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB)

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Kinetic characterization of wild-type and S229A mutant MurB: evidence for the role of Ser 229 as a general acid

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Characterization of NADP+ binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Spectroscopic properties of Escherichia coli UDP-N-acetylenolpyruvylglucosamine reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

4-Thiazolidinones: novel inhibitors of the bacterial enzyme MurB

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Identification and characterization of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from the Gram-positive pathogen Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

Cloning and identification of the Escherichia coli murB DNA sequence, which encodes UDP-N-acetylenolpyruvoylglucosamine reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2901076-4

7 January 2021

10.1016/S0960-894X(02)01076-4

Identifiers

DOI

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2 December 2017

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