Chronic heroin self-administration desensitizes mu opioid receptor-activated G-proteins in specific regions of rat brain. (Q44331908)

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7 November 2019

title

Chronic heroin self-administration desensitizes mu opioid receptor-activated G-proteins in specific regions of rat brain (English)

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7 November 2019

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L J Sim-Selley

1

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7 November 2019

D E Selley

2

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7 November 2019

L J Vogt

3

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7 November 2019

S R Childers

4

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7 November 2019

T J Martin

5

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7 November 2019

language of work or name

English

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publication date

1 June 2000

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7 November 2019

published in

Journal of Neuroscience

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7 November 2019

volume

20

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7 November 2019

page(s)

4555-4562

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7 November 2019

issue

12

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Anatomically distinct opiate receptor fields mediate reward and physical dependence.

7 November 2019

cites work

1 reference

12 December 2020

The mu-opioid receptor down-regulates differently from the delta-opioid receptor: requirement of a high affinity receptor/G protein complex formation

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Heroin addicts and methadone treatment in Albuquerque: a 22-year follow-up

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Morphine-induced desensitization and down-regulation at mu-receptors in 7315C pituitary tumor cells

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Stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding by endogenous opioids acting at a cloned mu receptor.

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Opiate receptor down-regulation and desensitization in neuroblastoma X glioma NG108-15 hybrid cells are two separate cellular adaptation processes

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Conditioned place preference: no tolerance to the rewarding properties of morphine.

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Non-competitive nature of the antagonistic mechanism responsible for tolerance development to opiate-induced analgesia

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Autoradiographic visualization in brain of receptor-G protein coupling using [35S]GTP gamma S binding

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Signal transduction correlates of mu opioid agonist intrinsic efficacy: receptor-stimulated [35S]GTP gamma S binding in mMOR-CHO cells and rat thalamus

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12 December 2020

A new method for receptor autoradiography: [3H]Opioid receptors in rat brain

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12 December 2020

The role of dopaminergic systems in opioid receptor desensitization in nucleus accumbens and caudate putamen of rat after chronic morphine treatment

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12 December 2020

Relationship of mu opioid receptor binding to activation of G-proteins in specific rat brain regions

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12 December 2020

mu-Opioid receptor-stimulated guanosine-5'-O-(gamma-thio)-triphosphate binding in rat thalamus and cultured cell lines: signal transduction mechanisms underlying agonist efficacy

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12 December 2020

Identification of opioid receptor-like (ORL1) peptide-stimulated [35S]GTP gamma S binding in rat brain.

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12 December 2020

Cloning and pharmacological characterization of a rat mu opioid receptor

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12 December 2020

Alkylation of mu opioid receptors by beta-funaltrexamine in vivo: comparison of the effects on in situ binding and heroin self-administration in rats

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12 December 2020

G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins

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12 December 2020

Light microscopic localization of brain opiate receptors: a general autoradiographic method which preserves tissue quality

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12 December 2020

Antisense mapping of MOR-1 in rats: distinguishing between morphine and morphine-6beta-glucuronide antinociception

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12 December 2020

mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain

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12 December 2020

Molecular mechanisms of drug addiction

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12 December 2020

Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat.

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12 December 2020

Acute and chronic effects of opioids on delta and mu receptor activation of G proteins in NG108-15 and SK-N-SH cell membranes

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12 December 2020

Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1.

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12 December 2020

Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment

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12 December 2020

Differences in G-protein activation by mu- and delta-opioid, and cannabinoid, receptors in rat striatum

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12 December 2020

G-protein-coupled receptor heterodimerization modulates receptor function

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12 December 2020

Opioid receptor regulation in mice.

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12 December 2020

Opioid receptor-coupled G-proteins in rat locus coeruleus membranes: decrease in activity after chronic morphine treatment

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12 December 2020

Simultaneous quantitative assessment of morphine tolerance and physical dependence

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12 December 2020

Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats

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12 December 2020

Chronic morphine increases mu-opiate receptor binding in rat brain: a quantitative autoradiographic study

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12 December 2020

Narcotic receptor sites in morphine-dependent rats.

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12 December 2020

Pharmacodynamics of subcutaneously administered diacetylmorphine, 6-acetylmorphine and morphine in mice

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12 December 2020

In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding

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12 December 2020

Evidence from opiate binding studies that heroin acts through its metabolites

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12 December 2020

Drug discrimination: no evidence for tolerance to opiates.

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12 December 2020

Cellular mechanisms of opioid tolerance: studies in single brain neurons

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12 December 2020

Differential Regulation by Guanine Nucleotides of Opiate Agonist and Antagonist Receptor Interactions

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12 December 2020

Opioid efficacy in a C6 glioma cell line stably expressing the delta opioid receptor.

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12 December 2020

Decrease in delta and mu opioid receptor binding capacity in rat brain after chronic etorphine treatment.

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12 December 2020

Effects of chronic morphine administration on mu opioid receptor-stimulated [35S]GTPgammaS autoradiography in rat brain

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12 December 2020

Modulation by mu-opioid agonists of guanosine-5'-O-(3-[35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells.

1 reference

12 December 2020

Molecular cloning and functional expression of a mu-opioid receptor from rat brain.

1 reference

12 December 2020

Chronic opioid treatment may uncouple opioid receptors and G-proteins: evidence from radiation inactivation analysis

1 reference

12 December 2020

The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization

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12 December 2020

Reinforcement processes in opiate addiction: a homeostatic model

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12 December 2020

Cloning of a delta opioid receptor by functional expression

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12 December 2020

Effects of chronic morphine exposure on opioid inhibition of adenylyl cyclase in 7315c cell membranes: a useful model for the study of tolerance at mu opioid receptors

1 reference

12 December 2020

Neurotransmitter turnover in rat striatum is correlated with morphine self-administration

1 reference

12 December 2020

10.1523/JNEUROSCI.20-12-04555.2000

Identifiers

DOI

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7 November 2019

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7 November 2019

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