PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction (Q44300437)

1 December 2017

PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction (English)

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1 December 2017

11

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1 December 2017

Harumi Suzuki

1

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1 December 2017

Satoshi Matsuda

2

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1 December 2017

Yasuo Terauchi

3

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1 December 2017

Mari Fujiwara

4

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1 December 2017

Toshiaki Ohteki

5

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1 December 2017

Tomoichiro Asano

6

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1 December 2017

Timothy W Behrens

7

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1 December 2017

Taku Kouro

8

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1 December 2017

Kiyoshi Takatsu

9

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1 December 2017

Takashi Kadowaki

10

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1 December 2017

language of work or name

English

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publication date

3 February 2003

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1 December 2017

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4

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1 December 2017

280-286

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3

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1 December 2017

Phosphoinositide kinases

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7 January 2021

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

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7 January 2021

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

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7 January 2021

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

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7 January 2021

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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7 January 2021

Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene

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7 January 2021

p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin

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7 January 2021

Signal transduction from the B cell antigen-receptor

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7 January 2021

Genetic analysis of B cell antigen receptor signaling

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7 January 2021

Regulation of B-cell activation and differentiation by the phosphatidylinositol 3-kinase and phospholipase Cgamma pathway

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7 January 2021

CD19 and CD22 regulate a B lymphocyte signal transduction pathway that contributes to autoimmunity

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7 January 2021

Btk and BLNK in B cell development

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7 January 2021

Mutation of the pleckstrin homology domain of Bruton's tyrosine kinase in immunodeficiency impaired inositol 1,3,4,5-tetrakisphosphate binding capacity

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7 January 2021

Btk function in B cell development and response.

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7 January 2021

Xid and Xid-like immunodeficiencies from a signaling point of view

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7 January 2021

BLNK: a central linker protein in B cell activation

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7 January 2021

BLNK: connecting Syk and Btk to calcium signals

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7 January 2021

Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

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7 January 2021

Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

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7 January 2021

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

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7 January 2021

Cellular survival: a play in three Akts

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7 January 2021

Akt signaling: linking membrane events to life and death decisions

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7 January 2021

PI3K: downstream AKTion blocks apoptosis

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7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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7 January 2021

Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle.

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7 January 2021

Reduced formation of phosphatidic acid upon B-cell receptor triggering of mouse B-lymphocytes lacking Bruton's tyrosine kinase

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7 January 2021

Induction of NF-kappaB by the Akt/PKB kinase

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7 January 2021

Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation

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7 January 2021

Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement

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7 January 2021

Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation

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7 January 2021

Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes

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7 January 2021

An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis

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7 January 2021

Transgene expression of bcl-xL permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells

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7 January 2021

Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.

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7 January 2021

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

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7 January 2021

Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha

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7 January 2021

Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt.

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7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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7 January 2021

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

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7 January 2021

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

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7 January 2021

Annexin V binds to viable B cells and colocalizes with a marker of lipid rafts upon B cell receptor activation

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7 January 2021

Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice

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7 January 2021

PI3K-mediated negative feedback regulation of IL-12 production in DCs

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7 January 2021

bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.

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7 January 2021

Identifiers

DOI

10.1038/NI890

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1 December 2017

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