The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1. (Q44279243)

1 December 2017

The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1. (English)

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1 December 2017

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3

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5

Melitta Schachner

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1 December 2017

Ina Kalus

1

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1 December 2017

Birthe Schnegelsberg

series ordinal

2

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1 December 2017

Ralf Kleene

series ordinal

4

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1 December 2017

language of work or name

English

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publication date

15 January 2003

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Journal of Biological Chemistry

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1 December 2017

278

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10381-10388

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12

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Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes

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Synaptic microenvironments--structural plasticity, adhesion molecules, proteases and their inhibitors

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Function of an axonal chemoattractant modulated by metalloprotease activity

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Regulated cleavage of a contact-mediated axon repellent

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Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice

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Calcium, protease activation, and cytoskeleton remodeling underlie growth cone formation and neuronal regeneration

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Extracellular serine protease neuropsin (KLK8) modulates neurite outgrowth and fasciculation of mouse hippocampal neurons in culture

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Proteolysis of glutamate receptor-interacting protein by calpain in rat brain: implications for synaptic plasticity

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Neural cell recognition molecule L1: from cell biology to human hereditary brain malformations

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Structural and functional evolution of the L1 family: are four adhesion molecules better than one?

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Expression of CHL1 and L1 by neurons and glia following sciatic nerve and dorsal root injury.

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Prevention of neuronal cell death by neural adhesion molecules L1 and CHL1.

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Role of L1 in neural development: what the knockouts tell us.

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Plasmin-sensitive dibasic sequences in the third fibronectin-like domain of L1-cell adhesion molecule (CAM) facilitate homomultimerization and concomitant integrin recruitment

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Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

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Biochemical characterization of different molecular forms of the neural cell adhesion molecule L1.

21 January 2018

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The third fibronectin type III repeat is required for L1 to serve as an optimal substratum for neurite extension

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Differential inhibition of neurone-neurone, neurone-astrocyte and astrocyte-astrocyte adhesion by L1, L2 and N-CAM antibodies.

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A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

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Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7

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Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

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Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions

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Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases

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Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines

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cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells.

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The neural recognition molecule L1 is a sialic acid-binding lectin for CD24, which induces promotion and inhibition of neurite outgrowth

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Lefty proteins exhibit unique processing and activate the MAPK pathway

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Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia

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The developmental expression in the rat CNS and peripheral tissues of proteases PC5 and PACE4 mRNAs: comparison with other proprotein processing enzymes.

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Immunohistochemical distribution of the prohormone convertase PC5-A in rat brain

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The pro-protein convertase PC1 is induced in the transected sciatic nerve and is present in cultured Schwann cells: comparison with PC5, furin and PC7, implication in pro-BDNF processing.

21 January 2018

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Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

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Structure-function analysis of cell adhesion by neural (N-) cadherin

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Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow

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Ultrastructure and function of dimeric, soluble intercellular adhesion molecule-1 (ICAM-1).

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Myelin protein zero exists as dimers and tetramers in native membranes of Xenopus laevis peripheral nerve

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CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated

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X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif

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Nectin: an adhesion molecule involved in formation of synapses

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Direct evidence for native CD4 oligomers in lymphoid and monocytoid cells

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Synaptic Strength as a Function of Post- versus Presynaptic Expression of the Neural Cell Adhesion Molecule NCAM

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21 January 2018

Identifiers

DOI

10.1074/JBC.M208351200

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1 December 2017

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