NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. (Q44263276)

1 December 2017

NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772878&resulttype=core&format=json

12 May 2020

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E D Foehr

1

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12 May 2020

X Lin

2

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12 May 2020

A O'Mahony

3

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12 May 2020

R Geleziunas

4

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12 May 2020

R A Bradshaw

5

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12 May 2020

W C Greene

6

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12 May 2020

language of work or name

English

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publication date

1 October 2000

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1 December 2017

Journal of Neuroscience

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12 May 2020

volume

20

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12 May 2020

issue

20

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12 May 2020

page(s)

7556-7563

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Keeping track of neurotrophin receptors

12 May 2020

cites work

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12 December 2020

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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12 December 2020

Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons

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12 December 2020

Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

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12 December 2020

The c-Jun transcription factor--bipotential mediator of neuronal death, survival and regeneration

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12 December 2020

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

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12 December 2020

Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation.

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12 December 2020

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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12 December 2020

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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12 December 2020

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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12 December 2020

The Trk family of neurotrophin receptors

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12 December 2020

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.

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12 December 2020

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

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12 December 2020

Free radicals, calcium, and the synaptic plasticity-cell death continuum: emerging roles of the transcription factor NF kappa B.

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12 December 2020

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

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12 December 2020

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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12 December 2020

p75 neurotrophin receptor expression on adult human oligodendrocytes: signaling without cell death in response to NGF

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12 December 2020

Comparison of the intracellular signaling responses by three chimeric fibroblast growth factor receptors in PC12 cells

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12 December 2020

TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction

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12 December 2020

N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

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12 December 2020

Association of the p75 neurotrophin receptor with TRAF6

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12 December 2020

Neurotrophin receptors: a window into neuronal differentiation

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12 December 2020

Signal transduction by the neurotrophin receptors

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12 December 2020

Potential involvement of the transcription factor NF-kappa B in neurological disorders

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12 December 2020

Decreased trkA gene expression within basal forebrain neurons in Alzheimer's disease.

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12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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12 December 2020

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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12 December 2020

Nerve growth factor activation of nuclear factor kappaB through its p75 receptor is an anti-apoptotic signal in RN22 schwannoma cells

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12 December 2020

Autoregulation of I kappa B alpha activity

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12 December 2020

Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

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12 December 2020

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

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12 December 2020

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

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12 December 2020

Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation

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12 December 2020

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

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12 December 2020

Identification and characterization of an IkappaB kinase

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12 December 2020

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

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12 December 2020

Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

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12 December 2020

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

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12 December 2020

Differential utilization of ShcA tyrosine residues and functional domains in the transduction of epidermal growth factor-induced mitogen-activated protein kinase activation in 293T cells and nerve growth factor-induced neurite outgrowth in PC12 cell

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12 December 2020

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

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12 December 2020

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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12 December 2020

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

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12 December 2020

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

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12 December 2020

Induction of apoptosis by the low-affinity NGF receptor

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12 December 2020

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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12 December 2020

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.

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12 December 2020

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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12 December 2020

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

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12 December 2020

Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma.

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12 December 2020

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

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12 December 2020

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

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12 December 2020

Inhibition of nuclear factor kappa B (NFkappaB) activity induces nerve growth factor-resistant apoptosis in PC12 cells

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12 December 2020

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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12 December 2020

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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12 December 2020

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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12 December 2020

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

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12 December 2020

p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor.

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12 December 2020

Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness.

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12 December 2020

Signalling through the neurotrophin receptor p75NTR.

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12 December 2020

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

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12 December 2020

Neurotrophins: the yin and yang of nerve growth factor

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12 December 2020

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

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12 December 2020

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

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12 December 2020

The NF-kappa B and I kappa B proteins: new discoveries and insights

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12 December 2020

Trophic factors and neuronal survival

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12 December 2020

Synaptic vesicle phosphoproteins and regulation of synaptic function

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12 December 2020

Regulation of neurotrophin receptors during the maturation of the mammalian visual system.

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12 December 2020

Dependence on p75 for innervation of some sympathetic targets.

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12 December 2020

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

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12 December 2020

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

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12 December 2020

10.1523/JNEUROSCI.20-20-07556.2000

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772878&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772878&resulttype=core&format=json

12 May 2020

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