Congenic D1A dopamine receptor mutants: ethologically based resolution of behavioural topography indicates genetic background as a determinant of knockout phenotype. (Q44259228)

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English	Congenic D1A dopamine receptor mutants: ethologically based resolution of behavioural topography indicates genetic background as a determinant of knockout phenotype.	scientific article

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16 December 2019

Congenic D1A dopamine receptor mutants: ethologically based resolution of behavioural topography indicates genetic background as a determinant of knockout phenotype (English)

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16 December 2019

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Fergal N McNamara

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16 December 2019

Jeremiah J Clifford

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Anthony Kinsella

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John Drago

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John L Waddington

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1 January 2003

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Neuropsychopharmacology

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1

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86-99

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16 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.npp.1300008

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The alleged dopamine D1 receptor agonist SKF 83959 is a dopamine D1 receptor antagonist in primate cells and interacts with other receptors

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Partial and full dopamine D1 receptor agonists in mice and rats: relation between behavioural effects and stimulation of adenylate cyclase activity in vitro

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Chipping away at complex behavior: transcriptome/phenotype correlations in the mouse brain

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Comparative, topographically-based evaluation of behavioural phenotype and specification of D(1)-like:D(2) interactions in a line of incipient congenic mice with D(2) dopamine receptor 'knockout'

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Topographical evaluation of the phenotype of spontaneous behaviour in mice with targeted gene deletion of the D1A dopamine receptor: paradoxical elevation of grooming syntax.

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21 January 2018

Conservation of behavioural topography to dopamine D1-like receptor agonists in mutant mice lacking the D1A receptor implicates a D1-like receptor not coupled to adenylyl cyclase.

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Topographical evaluation of behavioural phenotype in a line of mice with targeted gene deletion of the D2 dopamine receptor

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Genetics of mouse behavior: interactions with laboratory environment.

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Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies

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Action sequencing is impaired in D1A-deficient mutant mice

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Pharmacological characterization of behavioural responses to SK&F 83959 in relation to 'D1-like' dopamine receptors not linked to adenylyl cyclase

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Altered striatal function in a mutant mouse lacking D1A dopamine receptors

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Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

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Genetic modifiers of the insulin resistance phenotype in mice.

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Expression of striatal D1 dopamine receptors coupled to inositol phosphate production and Ca2+ mobilization in Xenopus oocytes

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Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor

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Modifier genes in mice and humans

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SKF83959 exhibits biochemical agonism by stimulating [(35)S]GTP gamma S binding and phosphoinositide hydrolysis in rat and monkey brain

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Complications associated with genetic background effects in research using knockout mice

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Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains

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Regional and strain-specific gene expression mapping in the adult mouse brain

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Influence of genetic background on knockout mouse phenotypes

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New insights into dopaminergic receptor function using antisense and genetically altered animals

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Behavioural assessment of mice lacking D1A dopamine receptors

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The psychopharmacology-molecular biology interface: exploring the behavioural roles of dopamine receptor subtypes using targeted gene deletion ('knockout').

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Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

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Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

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Stimulation of adenylate cyclase activity by benzazepine D-1 dopamine agonists with varying efficacies in the 6-hydroxydopamine lesioned rat--relationship to circling behaviour

1 reference

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7 January 2021

based on heuristic

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Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300008

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for a distinct D1-like dopamine receptor that couples to activation of phosphoinositide metabolism in brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300008

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.NPP.1300008

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12496944%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12496944%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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