Biomimetic membrane platform containing hERG potassium channel and its application to drug screening (Q44251312)

1 December 2017

Biomimetic membrane platform containing hERG potassium channel and its application to drug screening (English)

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1 December 2017

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Eva-Kathrin Sinner

3

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CongBao Kang

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CongBao Kang

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2

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author name string

Ahu Arslan Yildiz

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1

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PubMed ID

23423263

1 December 2017

language of work or name

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20 February 2013

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138

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7

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2007-2012

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The expression of outer membrane proteins for crystallization

1 December 2017

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

In vitro synthesis of protein in microbial systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Solving the membrane protein folding problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

The past, present and future of cell-free protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Evaluation of detergents for the soluble expression of alpha-helical and beta-barrel-type integral membrane proteins by a preparative scale individual cell-free expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Preparative scale cell-free expression systems: new tools for the large scale preparation of integral membrane proteins for functional and structural studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Preparation, functional characterization, and NMR studies of human KCNE1, a voltage-gated potassium channel accessory subunit associated with deafness and long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Allogeneic stimulation of cytotoxic T cells by supported planar membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Supported membranes: scientific and practical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Techniques for recording reconstituted ion channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Optical biosensors in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

hERG potassium channels and cardiac arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

[3H]dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

The [3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+]o

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Validation of a [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Identifying modulators of hERG channel activity using the PatchXpress planar patch clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Optimisation and validation of a medium-throughput electrophysiology-based hERG assay using IonWorks HT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Development of the predictor HERG fluorescence polarization assay using a membrane protein enrichment approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Incorporation of the HERG potassium channel in a mercury supported lipid bilayer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Cell-free synthesis of cytochrome bo(3) ubiquinol oxidase in artificial membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Biomimetic membrane platform: fabrication, characterization and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Predicting drug-hERG channel interactions that cause acquired long QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Functional and pharmacological properties of canine ERG potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

Role of hERG potassium channel assays in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3AN36159D

21 January 2018

Identifiers

DOI

10.1039/C3AN36159D

1 reference

1 December 2017

1 reference

PubMed ID

23423263