Assignment of molecular properties of a superactive coagulation factor VIIa variant to individual amino acid changes. (Q44224718)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12444984%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

title

Assignment of molecular properties of a superactive coagulation factor VIIa variant to individual amino acid changes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12444984%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1

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15 December 2019

author name string

Ole H Olsen

series ordinal

2

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15 December 2019

language of work or name

English

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publication date

1 December 2002

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12444984%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12444984%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

volume

269

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15 December 2019

issue

23

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15 December 2019

page(s)

5950-5955

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Structure of human factor VIIa and its implications for the triggering of blood coagulation

15 December 2019

cites work

1 reference

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Crystal structure of active site-inhibited human coagulation factor VIIa (des-Gla)

21 January 2018

1 reference

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Peptide exosite inhibitors of factor VIIa as anticoagulants

21 January 2018

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The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

21 January 2018

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Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03323.X

The factor VII zymogen structure reveals reregistration of beta strands during activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03323.X

Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity.

21 January 2018

1 reference

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Residue Met(156) contributes to the labile enzyme conformation of coagulation factor VIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03323.X

Substitution of valine for leucine 305 in factor VIIa increases the intrinsic enzymatic activity.

21 January 2018

1 reference

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Amino acid sequence and posttranslational modifications of human factor VIIa from plasma and transfected baby hamster kidney cells

21 January 2018

1 reference

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Structural changes in factor VIIa induced by Ca2+ and tissue factor studied using circular dichroism spectroscopy

21 January 2018

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Site-directed mutagenesis but not gamma-carboxylation of Glu-35 in factor VIIa affects the association with tissue factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03323.X

Substitution of aspartic acid for methionine-306 in factor VIIa abolishes the allosteric linkage between the active site and the binding interface with tissue factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03323.X

Identification of a calcium binding site in the protease domain of human blood coagulation factor VII: evidence for its role in factor VII-tissue factor interaction

21 January 2018

1 reference

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Role of zymogenicity-determining residues of coagulation factor VII/VIIa in cofactor interaction and macromolecular substrate recognition

21 January 2018

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Predicted solution structure of zymogen human coagulation FVII.

21 January 2018

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The tissue factor region that interacts with substrates factor IX and Factor X.

21 January 2018

1 reference

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The N-terminal epidermal growth factor-like domain in factor IX and factor X represents an important recognition motif for binding to tissue factor

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03323.X

Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa

21 January 2018

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Factor VIIa residue Arg290 is required for efficient activation of the macromolecular substrate factor X.

21 January 2018

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Cooperative interaction of divalent metal ions, substrate, and tissue factor with factor VIIa

21 January 2018

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Structurally and functionally distinct Ca2+ binding sites in the gamma-carboxyglutamic acid-containing domain of factor VIIa

21 January 2018

1 reference

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The location of the active site of blood coagulation factor VIIa above the membrane surface and its reorientation upon association with tissue factor. A fluorescence energy transfer study

21 January 2018

1 reference

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Substrate recognition by tissue factor-factor VIIa. Evidence for interaction of residues Lys165 and Lys166 of tissue factor with the 4-carboxyglutamate-rich domain of factor X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03323.X

Active site modification of factor VIIa affects interactions of the protease domain with tissue factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03323.X