Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia (Q44161647)

30 November 2017

Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia (English)

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30 November 2017

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Pérez-Galán P

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Marzo I

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Giraldo P

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Rubio-Félix D

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Lasierra P

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Larrad L

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Anel A

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Naval J

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1 October 2002

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2106-2114

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402650

30 November 2017

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Caspases influence the mode but not the extent of cell death induced by purine analogues in chronic lymphocytic leukaemia

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Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells

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Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells

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7 January 2021

Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway

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Detection of multiple antigens on western blots.

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Molecular characterization of mitochondrial apoptosis-inducing factor

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Mitoxantrone, a topoisomerase II inhibitor, induces apoptosis of B-chronic lymphocytic leukaemia cells

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7 January 2021

Doxorubicin and a butyric acid derivative effectively reduce levels of BCL-2 protein in the cells of chronic lymphocytic leukemia patient

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7 January 2021

2-Chlorodeoxyadenosine Chemotherapy Triggers Programmed Cell Death in Normal and Malignant Lymphocytes

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Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

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Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

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7 January 2021

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

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7 January 2021

Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells

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7 January 2021

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

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7 January 2021

Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c

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7 January 2021

Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway

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7 January 2021

Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine

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7 January 2021

Effects of 2-chlorodeoxyadenosine and gold sodium thiomalate on human bcl-2 gene expression

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7 January 2021

In vitro chemosensitivity of chronic lymphocytic leukaemia to purine analogues--correlation with clinical course

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7 January 2021

Fludarabine ability to down-regulate Bcl-2 gene product in CD5+ leukaemic B cells: in vitro/in vivo correlations

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7 January 2021

Flavopiridol circumvents Bcl-2 family mediated inhibition of apoptosis and drug resistance in B-cell chronic lymphocytic leukaemia

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7 January 2021

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402650

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30 November 2017

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