DNA damage and apoptosis in hydrogen peroxide-exposed Jurkat cells: bolus addition versus continuous generation of H(2)O(2). (Q44123333)

30 November 2017

DNA damage and apoptosis in hydrogen peroxide-exposed Jurkat cells: bolus addition versus continuous generation of H(2)O(2). (English)

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30 November 2017

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Alexandra Barbouti

1

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30 November 2017

Paschalis-Thomas Doulias

2

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30 November 2017

Lambros Nousis

3

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30 November 2017

Margarita Tenopoulou

4

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30 November 2017

Dimitrios Galaris

5

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30 November 2017

language of work or name

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1 September 2002

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Free Radical Biology and Medicine

30 November 2017

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30 November 2017

33

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30 November 2017

5

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30 November 2017

691-702

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Oxidants, antioxidants, and the degenerative diseases of aging

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H(2)O(2)-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells

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Cellular titration of apoptosis with steady state concentrations of H(2)O(2): submicromolar levels of H(2)O(2) induce apoptosis through Fenton chemistry independent of the cellular thiol state

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Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation

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Triggering and modulation of apoptosis by oxidative stress

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Lysosomal involvement in apoptosis

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Calcium chelator Quin 2 prevents hydrogen-peroxide-induced DNA breakage and cytotoxicity

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Glucose oxidase-produced H2O2 induces Ca2+-dependent DNA damage in human peripheral blood lymphocytes

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Intracellular iron, but not copper, plays a critical role in hydrogen peroxide-induced DNA damage.

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Caspase-dependent and -independent events in apoptosis induced by hydrogen peroxide

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Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide

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Hydroperoxide metabolism in mammalian organs

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Trimetazidine protects low-density lipoproteins from oxidation and cultured cells exposed to H(2)O(2) from DNA damage.

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Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo

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Oxidative stress inhibits apoptosis in human lymphoma cells

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Oxidants as stimulators of signal transduction

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Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells

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DOI

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30 November 2017

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