Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation (Q44107506)

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scientific article published on September 1, 2003

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English	Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation	scientific article published on September 1, 2003

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scholarly article

1 reference

Europe PubMed Central

29 November 2017

Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation (English)

1 reference

Europe PubMed Central

29 November 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

10.1182/BLOOD-2003-02-0489

https://api.crossref.org/works/10.1182/BLOOD-2003-02-0489

30 December 2023

1 reference

10.1182/BLOOD-2003-02-0489

https://api.crossref.org/works/10.1182/BLOOD-2003-02-0489

30 December 2023

1 reference

10.1182/BLOOD-2003-02-0489

https://api.crossref.org/works/10.1182/BLOOD-2003-02-0489

30 December 2023

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object named as

Joseph H Antin

1 reference

Europe PubMed Central

29 November 2017

Stephanie J. Lee

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object named as

Stephanie J Lee

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Europe PubMed Central

29 November 2017

author name string

Corey Cutler

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1 reference

Europe PubMed Central

29 November 2017

Haesook T. Kim

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730113

30 December 2023

Vincent T. Ho

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1 reference

Europe PubMed Central

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30 December 2023

David B. Miklos

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Europe PubMed Central

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30 December 2023

Ephraim P. Hochberg

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1 reference

Europe PubMed Central

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30 December 2023

Catherine J. Wu

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730113

30 December 2023

Edwin P. Alyea

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730113

30 December 2023

Robert J. Soiffer

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Europe PubMed Central

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publication date

1 May 2003

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Europe PubMed Central

29 November 2017

1 September 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12730113

30 December 2023

full work available at URL

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Europe PubMed Central

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102

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1601-1605

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Europe PubMed Central

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Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group

1

1 reference

10.1182/BLOOD-2003-02-0489

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Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study

2

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Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

3

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Sirolimus-tacrolimus combination immunosuppression

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CD4+ and CD8+ T cells each can utilize a perforin-dependent pathway to mediate lethal graft-versus-host disease in major histocompatibility complex-disparate recipients

6

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Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease

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Synergistic mechanisms by which sirolimus and cyclosporin inhibit rat heart and kidney allograft rejection

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Combined effect of rapamycin and FK 506 in prolongation of small bowel graft survival in the mouse

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Synergistic effect of rapamycin and cyclosporine in prevention of acute kidney allograft rejection in the mouse

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Effect of tacrolimus (FK506) and sirolimus (rapamycin) mono- and combination therapy in prolongation of renal allograft survival in the monkey

11

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Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after HLA-mismatched marrow or blood stem cell transplantation.

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Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia

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Allogeneic bone marrow transplantation for chronic myelogenous leukemia: comparative analysis of unrelated versus matched sibling donor transplantation

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Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age

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Effect of HLA matching on outcome of related and unrelated donor transplantation therapy for chronic myelogenous leukemia

22

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Effect of HLA class II gene disparity on clinical outcome in unrelated donor hematopoietic cell transplantation for chronic myeloid leukemia: the US National Marrow Donor Program Experience

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Unrelated donor marrow transplantation for myelodysplastic syndromes: outcome analysis in 510 transplants facilitated by the National Marrow Donor Program

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Rapamune® (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression

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Combined costimulation blockade plus rapamycin but not cyclosporine produces permanent engraftment

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Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

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Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

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Prevention of graft versus host disease by inactivation of host antigen-presenting cells

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APCs in the liver and spleen recruit activated allogeneic CD8+ T cells to elicit hepatic graft-versus-host disease

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Rapamycin impairs antigen uptake of human dendritic cells

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Rapamycin inhibits IL-4--induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo

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Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression

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Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation

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The side effect profile of sirolimus: a phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients

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Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group

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Efficacy of sirolimus (rapamycin) administered concomitantly with a subtherapeutic dose of cyclosporin in the treatment of severe psoriasis: a randomized controlled trial

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Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation

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10.1182/BLOOD-2003-02-0489

1 reference

Europe PubMed Central

29 November 2017

1 reference

Europe PubMed Central

29 November 2017

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