N-Ethylmaleimide inhibits platelet-derived growth factor BB-stimulated Akt phosphorylation via activation of protein phosphatase 2A. (Q44097428)

29 November 2017

N-Ethylmaleimide inhibits platelet-derived growth factor BB-stimulated Akt phosphorylation via activation of protein phosphatase 2A. (English)

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29 November 2017

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Chandrahasa R Yellaturu

1

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29 November 2017

Manjula Bhanoori

2

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29 November 2017

Indira Neeli

3

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29 November 2017

Gadiparthi N Rao

4

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29 November 2017

language of work or name

English

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publication date

8 August 2002

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Journal of Biological Chemistry

29 November 2017

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29 November 2017

277

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29 November 2017

40148-40155

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29 November 2017

42

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Activation of the OxyR transcription factor by reversible disulfide bond formation

29 November 2017

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Redox regulation of transcriptional activators

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Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation

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Redox regulation of p53 during hypoxia

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Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

21 January 2018

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Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C.

21 January 2018

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Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha.

21 January 2018

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JunB forms the majority of the AP-1 complex and is a target for redox regulation by receptor tyrosine kinase and G protein-coupled receptor agonists in smooth muscle cells

21 January 2018

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Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

21 January 2018

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Human fat cells possess a plasma membrane-bound H2O2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase

21 January 2018

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Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha.

21 January 2018

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21 January 2018

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Regulation of cell function by methionine oxidation and reduction

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Regulation of the yeast Yap1p nuclear export signal is mediated by redox signal-induced reversible disulfide bond formation

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Disulfide bond formation in the Escherichia coli cytoplasm: an in vivo role reversal for the thioredoxins

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Redox potentials of glutaredoxins and other thiol-disulfide oxidoreductases of the thioredoxin superfamily determined by direct protein-protein redox equilibria

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Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor

21 January 2018

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Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade

21 January 2018

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Oxidants, antioxidants, and the degenerative diseases of aging

21 January 2018

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Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.

21 January 2018

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The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

21 January 2018

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

21 January 2018

1 reference

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Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

21 January 2018

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21 January 2018

Tissue sulfhydryl groups

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Three thiol groups are important for the activity of the liver microsomal glucose-6-phosphatase system. Unusual behavior of one thiol located in the glucose-6-phosphate translocase.

21 January 2018

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FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

21 January 2018

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Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

21 January 2018

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Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

21 January 2018

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Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells.

21 January 2018

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Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities

21 January 2018

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Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k

21 January 2018

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Mitochondrial control of cell death

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

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Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A.

21 January 2018

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Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis.

21 January 2018

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Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation

21 January 2018

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Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid

21 January 2018

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The predicted beta12-beta13 loop is important for inhibition of PP2Acalpha by the antitumor drug fostriecin

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Cytoskeletal integrity in interphase cells requires protein phosphatase activity

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Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis

21 January 2018

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Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.

21 January 2018

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Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides production

21 January 2018

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VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release

21 January 2018

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Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

21 January 2018

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

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Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

21 January 2018

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Studies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of pp70 S6 kinase

21 January 2018

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Rapid induction of apoptosis mediated by peptides that bind initiation factor eIF4E.

21 January 2018

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Overexpression of calreticulin modulates protein kinase B/Akt signaling to promote apoptosis during cardiac differentiation of cardiomyoblast H9c2 cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M206376200

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29 November 2017

1 reference