Studies on neuronal death in the mouse model of Niemann-Pick C disease (Q44059850)

29 November 2017

title

Studies on neuronal death in the mouse model of Niemann-Pick C disease (English)

1 reference

Niemann–Pick disease, type C

29 November 2017

main subject

1 reference

Robert P Erickson

1

1 reference

29 November 2017

Ora Bernard

series ordinal

2

1 reference

29 November 2017

publication date

1 June 2002

1 reference

Journal of Neuroscience Research

29 November 2017

published in

1 reference

29 November 2017

volume

68

1 reference

29 November 2017

issue

6

1 reference

29 November 2017

page(s)

738-744

1 reference

The Bcl-2 protein family: arbiters of cell survival

29 November 2017

cites work

1 reference

Relation Between Lipophilicity and Pharmacological Behavior of Minocycline, Doxycycline, Tetracycline, and Oxytetracycline in Dogs

21 January 2018

1 reference

NSE-bcl-2 transgenic mice, a model system for studying neuronal death and survival.

21 January 2018

1 reference

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

21 January 2018

1 reference

bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations

21 January 2018

1 reference

Transport-Dependent Proteolysis of SREBP

21 January 2018

1 reference

Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

21 January 2018

1 reference

Pharmacological and genetic modifications of somatic cholesterol do not substantially alter the course of CNS disease in Niemann-Pick C mice.

21 January 2018

1 reference

bcl-2 transgene expression can protect neurons against developmental and induced cell death

21 January 2018

1 reference

Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control

21 January 2018

1 reference

Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease

21 January 2018

1 reference

Type C Niemann-Pick disease: a murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in liver

21 January 2018

1 reference

Functions of ceramide in coordinating cellular responses to stress

21 January 2018

1 reference

Bcl-2 overexpression protects the neonatal cerebellum from ethanol neurotoxicity.

21 January 2018

1 reference

Cerebellar degeneration in the Niemann-Pick type C mouse.

21 January 2018

1 reference

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

21 January 2018

1 reference

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

21 January 2018

1 reference

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

21 January 2018

1 reference

Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity

21 January 2018

1 reference

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

21 January 2018

1 reference

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

1 reference

Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease

21 January 2018

1 reference

PML induces a novel caspase-independent death process

21 January 2018

1 reference

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-X(L) gene expression

21 January 2018

1 reference

The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

21 January 2018

1 reference

21 January 2018

Caspases: enemies within

1 reference

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

21 January 2018

1 reference

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

21 January 2018

1 reference

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

21 January 2018

1 reference

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

Increased cerebellar Purkinje cell numbers in mice overexpressing a human bcl-2 transgene.

21 January 2018

1 reference

Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations

21 January 2018

1 reference

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

21 January 2018

1 reference

Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice

21 January 2018

1 reference

Ceramide and its interconvertible metabolite sphingosine function as indispensable lipid factors involved in survival and dendritic differentiation of cerebellar Purkinje cells.

21 January 2018

1 reference

Neurotrophic factors prevent ceramide-induced apoptosis downstream of c-Jun N-terminal kinase activation in PC12 cells.

21 January 2018

1 reference

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

21 January 2018

1 reference

Suppression of bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JNR.10257

1 reference

29 November 2017

1 reference