VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism (Q44043571)

29 November 2017

VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism (English)

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29 November 2017

9

Napoleone Ferrara

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29 November 2017

Hans-Peter Gerber

1

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29 November 2017

Ajay K Malik

2

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29 November 2017

Gregg P Solar

3

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29 November 2017

Daniel Sherman

4

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29 November 2017

Xiao Huan Liang

5

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29 November 2017

Gloria Meng

6

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29 November 2017

Kyu Hong

7

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29 November 2017

James C Marsters

8

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29 November 2017

language of work or name

English

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publication date

1 June 2002

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29 November 2017

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29 November 2017

417

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29 November 2017

954-958

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29 November 2017

6892

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https://scigraph.springernature.com/pub.10.1038/nature00821

29 November 2017

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cites work

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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Autocrine/paracrine mechanisms in human hematopoiesis

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7 January 2021

Expression and secretion of vascular endothelial growth factor-A by cytokine-stimulated hematopoietic progenitor cells. Possible role in the hematopoietic microenvironment

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7 January 2021

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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7 January 2021

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Mechanism of autocrine stimulation in hematopoietic cells producing interleukin-3 after retrovirus-mediated gene transfer

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Cytokine and chemokine production by CD34+ haemopoietic progenitor cells: detection in single cells

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes.

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

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https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemia blasts

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00821

7 January 2021

Identifiers

DOI

10.1038/NATURE00821

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Dimensions Publication ID

29 November 2017

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