Reduced flavins promote oxidative DNA damage in non-respiring Escherichia coli by delivering electrons to intracellular free iron (Q44038769)

29 November 2017

Reduced flavins promote oxidative DNA damage in non-respiring Escherichia coli by delivering electrons to intracellular free iron (English)

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29 November 2017

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Anh N Woodmansee

1

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PubMed ID

12080063

29 November 2017

James A Imlay

series ordinal

2

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PubMed ID

12080063

29 November 2017

language of work or name

English

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publication date

21 June 2002

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Journal of Biological Chemistry

29 November 2017

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29 November 2017

277

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29 November 2017

34055-34066

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29 November 2017

37

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The production of superoxide anion radicals in the reaction of reduced flavins and flavoproteins with molecular oxygen

29 November 2017

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Alkyl hydroperoxide reductase is the primary scavenger of endogenous hydrogen peroxide in Escherichia coli

21 January 2018

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Iron homeostasis, oxidative stress, and DNA damage

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203977200

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

21 January 2018

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Cells transfected with transferrin receptor cDNA lacking the iron regulatory domain become more sensitive to the DNA-damaging action of oxidative stress.

21 January 2018

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Lethal oxidative damage and mutagenesis are generated by iron in delta fur mutants of Escherichia coli: protective role of superoxide dismutase

21 January 2018

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Superoxide accelerates DNA damage by elevating free-iron levels

21 January 2018

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Superoxide-dependent production of hydroxyl radical catalyzed by iron-EDTA complex

21 January 2018

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Polarographic assay and intracellular distribution of superoxide dismutase in rat liver

21 January 2018

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Oxygen-dependent mutagenesis in Escherichia coli lacking superoxide dismutase

21 January 2018

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Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203977200

DNA damage and oxygen radical toxicity

21 January 2018

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Bimodal pattern of killing of DNA-repair-defective or anoxically grown Escherichia coli by hydrogen peroxide

21 January 2018

1 reference

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Characterization of 4-hydroxyphenylacetate 3-hydroxylase (HpaB) of Escherichia coli as a reduced flavin adenine dinucleotide-utilizing monooxygenase

21 January 2018

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Mutagenesis and stress responses induced in Escherichia coli by hydrogen peroxide

21 January 2018

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Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

21 January 2018

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Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

21 January 2018

1 reference

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Hydrogen peroxide fluxes and compartmentalization inside growing Escherichia coli

21 January 2018

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Superoxide and the production of oxidative DNA damage

21 January 2018

1 reference

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Vibrio harveyi NADPH-flavin oxidoreductase: cloning, sequencing and overexpression of the gene and purification and characterization of the cloned enzyme

21 January 2018

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Purification of the two-enzyme system catalyzing the oxidation of the D-proline residue of pristinamycin IIB during the last step of pristinamycin IIA biosynthesis

21 January 2018

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Cloning, sequencing, and analysis of a gene cluster from Chelatobacter heintzii ATCC 29600 encoding nitrilotriacetate monooxygenase and NADH:flavin mononucleotide oxidoreductase

21 January 2018

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Identification and characterization of the two-enzyme system catalyzing oxidation of EDTA in the EDTA-degrading bacterial strain DSM 9103

21 January 2018

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Gene overexpression, purification, and identification of a desulfurization enzyme from Rhodococcus sp. strain IGTS8 as a sulfide/sulfoxide monooxygenase

21 January 2018

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Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli

21 January 2018

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Functional analysis of the small component of the 4-hydroxyphenylacetate 3-monooxygenase of Escherichia coli W: a prototype of a new Flavin:NAD(P)H reductase subfamily

21 January 2018

1 reference

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Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the enzyme

21 January 2018

1 reference

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Ferric reductases or flavin reductases?

21 January 2018

1 reference

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Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: an ESR spin trapping study

21 January 2018

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Differential transfers of reduced flavin cofactor and product by bacterial flavin reductase to luciferase

21 January 2018

1 reference

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Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis

21 January 2018

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The mechanism and substrate specificity of the NADPH:flavin oxidoreductase from Escherichia coli.

21 January 2018

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Nitric oxide potentiates hydrogen peroxide-induced killing of Escherichia coli.

21 January 2018

1 reference

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Yeast lacking superoxide dismutase(s) show elevated levels of "free iron" as measured by whole cell electron paramagnetic resonance

21 January 2018

1 reference

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Flavin radicals: chemistry and biochemistry

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M203977200

1 reference

29 November 2017

1 reference

PubMed ID

12080063