Thrombin-stimulated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases (Q44034946)

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English	Thrombin-stimulated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 November 2017

Thrombin-stimulated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases (English)

1 reference

Europe PubMed Central

29 November 2017

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phosphorylation

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author name string

Rosemary J Keogh

1

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Europe PubMed Central

29 November 2017

Rebecca A Houliston

2

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Europe PubMed Central

29 November 2017

Caroline P D Wheeler-Jones

3

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Europe PubMed Central

29 November 2017

language of work or name

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publication date

1 June 2002

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Europe PubMed Central

29 November 2017

Biochemical and Biophysical Research Communications

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Europe PubMed Central

29 November 2017

294

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Europe PubMed Central

29 November 2017

5

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Europe PubMed Central

29 November 2017

1001-1008

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Europe PubMed Central

29 November 2017

Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway

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G protein-coupled receptors control vascular smooth muscle cell proliferation via pp60c-src and p21ras

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The roles of protein kinase C and intracellular Ca2+ in the secretion of von Willebrand factor from human vascular endothelial cells

1 reference

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Human endothelial Pyk2 is expressed in two isoforms and associates with paxillin and p130Cas

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Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily

1 reference

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Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades

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Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

1 reference

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Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha

1 reference

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Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions

1 reference

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Interaction of two proline-rich sequences of cell adhesion kinase beta with SH3 domains of p130Cas-related proteins and a GTPase-activating protein, Graf

1 reference

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Protein tyrosine kinases regulate agonist-stimulated prostacyclin release but not von Willebrand factor secretion from human umbilical vein endothelial cells

1 reference

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Inhibition of MAP kinase kinase (MEK) blocks endothelial PGI2 release but has no effect on von Willebrand factor secretion or E-selectin expression

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

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Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

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An endothelial cell growth factor from bovine hypothalamus: identification and partial characterization

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

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Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton

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A role for PYK2 in regulation of ERK1/2 MAP kinases and PI 3-kinase by ANG II in vascular smooth muscle

1 reference

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7 January 2021

Calcium- and protein kinase C-dependent activation of the tyrosine kinase PYK2 by angiotensin II in vascular smooth muscle

1 reference

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7 January 2021

Regulation of calcium-sensitive tyrosine kinase Pyk2 by angiotensin II in endothelial cells. Roles of Yes tyrosine kinase and tyrosine phosphatase SHP-2

1 reference

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7 January 2021

Outside-in signaling pathway linked to CD146 engagement in human endothelial cells

1 reference

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RAFTK/Pyk2-mediated cellular signalling

1 reference

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3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors block calcium-dependent tyrosine kinase Pyk2 activation by angiotensin II in vascular endothelial cells. involvement of geranylgeranylation of small G protein Rap1.

1 reference

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Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

1 reference

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7 January 2021

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10.1016/S0006-291X(02)00568-5

1 reference

Europe PubMed Central

29 November 2017

1 reference

Europe PubMed Central

29 November 2017

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