Involvement of thioredoxin-interacting protein (TXNIP) in glucocorticoid-mediated beta cell death (Q44030506)

29 November 2017

Involvement of thioredoxin-interacting protein (TXNIP) in glucocorticoid-mediated beta cell death (English)

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29 November 2017

E Reich

1

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29 November 2017

A Tamary

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2

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29 November 2017

R Vogt Sionov

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3

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29 November 2017

D Melloul

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4

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29 November 2017

14 January 2012

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29 November 2017

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29 November 2017

55

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29 November 2017

4

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29 November 2017

1048-1057

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https://scigraph.springernature.com/pub.10.1007/s00125-011-2422-z

29 November 2017

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Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats

21 January 2018

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Novel insights into glucocorticoid-mediated diabetogenic effects: towards expansion of therapeutic options?

21 January 2018

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Type 2 diabetes-a matter of beta-cell life and death?

21 January 2018

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Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids.

21 January 2018

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Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets

21 January 2018

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Insulin resistant subjects lack islet adaptation to short-term dexamethasone-induced reduction in insulin sensitivity.

21 January 2018

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The effects of dexamethasone on insulin release and biosynthesis are dependent on the dose and duration of treatment

21 January 2018

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Acute and 2-week exposure to prednisolone impair different aspects of beta-cell function in healthy men.

21 January 2018

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Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans.

21 January 2018

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Beta-cell development: the role of intercellular signals

21 January 2018

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Dissecting the role of glucocorticoids on pancreas development

21 January 2018

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Identification of the human insulin negative regulatory element as a negative glucocorticoid response element.

21 January 2018

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Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1

21 January 2018

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Dexamethasone suppresses phospholipase C activation and insulin secretion from isolated rat islets

21 January 2018

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Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4.

21 January 2018

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Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3

21 January 2018

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Regulatory roles of thioredoxin in oxidative stress-induced cellular responses

21 January 2018

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Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2422-Z

Lack of TXNIP protects beta-cells against glucotoxicity

21 January 2018

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Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets

21 January 2018

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Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells

21 January 2018

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Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

21 January 2018

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Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death

21 January 2018

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Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis

21 January 2018

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Protein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations

21 January 2018

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Thioredoxin-binding protein-2 (TBP-2/VDUP1/TXNIP) regulates T-cell sensitivity to glucocorticoid during HTLV-I-induced transformation

21 January 2018

1 reference

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Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

21 January 2018

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IGF-1 protects against dexamethasone-induced cell death in insulin secreting INS-1 cells independent of AKT/PKB phosphorylation

21 January 2018

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Aged transgenic mice with increased glucocorticoid sensitivity in pancreatic beta-cells develop diabetes

21 January 2018

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Inhibition by corticosterone of calcium inflow and insulin release in rat pancreatic islets

21 January 2018

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Effect of adrenal steroids on insulin release from cultured rat islets of Langerhans

21 January 2018

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Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion

21 January 2018

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Inhibition of forkhead box O1 protects pancreatic beta-cells against dexamethasone-induced dysfunction

21 January 2018

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Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway

21 January 2018

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Decreasing Txnip mRNA and protein levels in pancreatic MIN6 cells reduces reactive oxygen species and restores glucose regulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2422-Z

Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2422-Z

Transgenic expression of antioxidant protein thioredoxin in pancreatic beta cells prevents progression of type 2 diabetes mellitus.

21 January 2018

1 reference

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Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression

21 January 2018

1 reference

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The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

21 January 2018

1 reference

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Thioredoxin-binding protein-2-like inducible membrane protein is a novel vitamin D3 and peroxisome proliferator-activated receptor (PPAR)gamma ligand target protein that regulates PPARgamma signaling

21 January 2018

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Cyclic AMP signaling stimulates proteasome degradation of thioredoxin interacting protein (TxNIP) in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2422-Z

Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2422-Z

p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells

21 January 2018

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Glucocorticoids: extensive physiological actions modulated through multiple mechanisms of gene regulation.

21 January 2018

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Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2422-Z

Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis

21 January 2018

1 reference

12 December 2020

Glucocorticoid increases glucose cycling and inhibits insulin release in pancreatic islets of ob/ob mice

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12 December 2020

Direct long-term effect of hydrocortisone on insulin and glucagon release from mouse pancreatic islets in tissue culture

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12 December 2020

Glucocorticoids impair fetal beta-cell development in rats.

1 reference

12 December 2020

Prolactin, progesterone, and dexamethasone coordinately and adversely regulate glucokinase and cAMP/PDE cascades in MIN6 β-cells

1 reference

12 December 2020

10.1007/S00125-011-2422-Z

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release_alem42rlr5emlpvnsi3ijp5kce

29 November 2017

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https://api.fatcat.wiki/v0/release/alem42rlr5emlpvnsi3ijp5kce

24 November 2022

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