Effect of endotoxin on doxorubicin transport across blood-brain barrier and P-glycoprotein function in mice (Q44028369)

29 November 2017

Effect of endotoxin on doxorubicin transport across blood-brain barrier and P-glycoprotein function in mice (English)

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29 November 2017

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Ying Lan Zhao

1

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29 November 2017

Jun Du

2

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29 November 2017

Hiroaki Kanazawa

3

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29 November 2017

Ayako Sugawara

4

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29 November 2017

Kenji Takagi

5

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29 November 2017

Kiyoyuki Kitaichi

6

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29 November 2017

Yasuaki Tatsumi

7

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29 November 2017

Kenzo Takagi

8

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29 November 2017

Takaaki Hasegawa

9

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29 November 2017

language of work or name

English

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publication date

1 June 2002

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European Journal of Pharmacology

29 November 2017

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29 November 2017

445

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29 November 2017

1-2

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29 November 2017

115-123

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Effect of endotoxin on P-glycoprotein-mediated biliary and renal excretion of rhodamine-123 in rats

29 November 2017

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Disposition of 14C-labelled 4'-epidoxorubicin and doxorubicin in the rat. A comparative study

7 January 2021

1 reference

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Metabolism of doxorubicin and epirubicin in adult human hepatocytes in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

No increase in blood-brain barrier permeability after intraperitoneal injection of endotoxin in the rat.

7 January 2021

1 reference

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Inhibition of nitric oxide synthase attenuates blood-brain barrier disruption during experimental meningitis.

7 January 2021

1 reference

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A defect of lipopolysaccharide-induced nitric oxide synthase gene expression in the paraventricular nucleus of Lewis rats

7 January 2021

1 reference

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Transport of a hydrophilic compound into the cerebrospinal fluid during experimental allergic encephalomyelitis and after lipopolysaccharide administration.

7 January 2021

1 reference

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The biochemistry of P-glycoprotein-mediated multidrug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Inhibition of P-glycoprotein: rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Agonists and antagonists for lipopolysaccharide-induced cytokines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Hepatic microsomal drug metabolism after administration of endotoxin in rats

7 January 2021

1 reference

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Effect of a bacterial lipopolysaccharide on biliary excretion of a beta-lactam antibiotic, cefoperazone, in rats

7 January 2021

1 reference

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Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice.

7 January 2021

1 reference

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Modulation of doxorubicin concentration by cyclosporin A in brain and testicular barrier tissues expressing P-glycoprotein in rats

7 January 2021

1 reference

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

7 January 2021

1 reference

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Decreased antipyrine clearance following endotoxin administration: in vivo evidence of the role of nitric oxide.

7 January 2021

1 reference

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The expression of tumour necrosis factor in the hypothalamus after treatment with lipopolysaccharide.

7 January 2021

1 reference

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Methylene blue inhibits the increase of inducible nitric oxide synthase activity induced by stress and lipopolysaccharide in the medial basal hypothalamus of rats.

7 January 2021

1 reference

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Effect of lipopolysaccharide on the permeability and reactivity of the cerebral microcirculation: role of inducible nitric oxide synthase.

7 January 2021

1 reference

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Molecular-weight-dependent pharmacokinetics of fluorescein-labeled dextrans in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Regulation of cytochromes P450 during inflammation and infection.

7 January 2021

1 reference

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Multidrug resistance gene (MDR1) expression in human brain tumors

7 January 2021

1 reference

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Influence of a bacterial lipopolysaccharide on the pharmacokinetics of tobramycin in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Alterations in pharmacokinetics and protein binding behavior of cefazolin in endotoxemic rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Alterations in renal uptake kinetics of the xanthine derivative enprofylline in endotoxaemic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Time-dependent effects of Klebsiella pneumoniae endotoxin on hepatic drug-metabolizing enzyme activity in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Endotoxin impairs biliary transport of sparfloxacin and its glucuronide in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

In vivo and in vitro evidence for ATP-dependency of P-glycoprotein-mediated efflux of doxorubicin at the blood-brain barrier.

7 January 2021

1 reference

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Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier

7 January 2021

1 reference

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Lipopolysaccharide evokes the modulation of brain cytochrome P4501A in the rat.

7 January 2021

1 reference

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New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy.

7 January 2021

1 reference

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Cyclosporin A inhibits the extrusion pump function of p-glycoprotein in the inner ear of mice treated with vinblastine and doxorubicin

7 January 2021

1 reference

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

7 January 2021

1 reference

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Nitric oxide modulates blood-brain barrier permeability during infections with an inactivated bacterium.

7 January 2021

1 reference

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Endotoxin downregulates hepatic expression of P-glycoprotein and MRP2 in 2-acetylaminofluorene-treated rats

7 January 2021

1 reference

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Disposition and metabolism of adriamycin in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901661-8

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

7 January 2021

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P-glycoprotein-mediated efflux transport of anticancer drugs at the blood-brain barrier.

7 January 2021

1 reference

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Mechanisms of multidrug resistance and implications for therapy

7 January 2021

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Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver

7 January 2021

1 reference

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The effect of lipopolysaccharide on the disposition of xanthines in rats

7 January 2021

1 reference

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Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorubicin in non-human primates.

7 January 2021

1 reference

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Brain bilirubin content is increased in P-glycoprotein-deficient transgenic null mutant mice.

7 January 2021

1 reference

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Metabolism of 4'-modified analogs of doxorubicin. unique glucuronidation pathway for 4'-epidoxorubicin

7 January 2021

1 reference

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Disruption of mdr1a p-glycoprotein gene results in dysfunction of blood-inner ear barrier in mice

7 January 2021

1 reference

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Possible involvement of P-glycoprotein in the biliary excretion of grepafloxacin

7 January 2021

1 reference

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10.1016/S0014-2999(02)01661-8

7 January 2021

Identifiers

DOI

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29 November 2017

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