The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma (Q44010949)

28 November 2017

The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma (English)

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28 November 2017

Orlie Kahana

1

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28 November 2017

Michael Micksche

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2

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28 November 2017

Isaac P Witz

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3

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28 November 2017

Ilana Yron

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4

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28 November 2017

language of work or name

English

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publication date

1 June 2002

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28 November 2017

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28 November 2017

21

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28 November 2017

25

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28 November 2017

3969-3977

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205472

28 November 2017

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cites work

Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

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Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines

21 January 2018

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Intrinsic MDR-1 gene and P-glycoprotein expression in human melanoma cell lines.

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Possible role of the multidrug resistance-associated protein (MRP) in chemoresistance of human melanoma cells

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Molecular classification of cutaneous malignant melanoma by gene expression profiling

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Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

21 January 2018

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Genomic analysis of metastasis reveals an essential role for RhoC

21 January 2018

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Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

21 January 2018

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Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

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Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

21 January 2018

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Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

21 January 2018

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Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase

21 January 2018

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Integrins: versatility, modulation, and signaling in cell adhesion

21 January 2018

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

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Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

21 January 2018

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

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Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.

21 January 2018

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Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation

21 January 2018

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The microenvironment of the tumour-host interface

21 January 2018

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Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

21 January 2018

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Requirement for focal adhesion kinase in tumor cell adhesion

21 January 2018

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Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate

21 January 2018

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Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase

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Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins

21 January 2018

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Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement

21 January 2018

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Identification of integrin-stimulated sites of serine phosphorylation in FRNK, the separately expressed C-terminal domain of focal adhesion kinase: a potential role for protein kinase A.

21 January 2018

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Rho GTPases. Integrating integrin signaling

21 January 2018

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Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src

21 January 2018

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Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

21 January 2018

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

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Signaling through focal adhesion kinase

21 January 2018

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Integrins, oncogenes, and anchorage independence.

21 January 2018

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Integrins: emerging paradigms of signal transduction

21 January 2018

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Signaling networks linking integrins and rho family GTPases.

21 January 2018

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Respiratory infections. An opportunity for integrated disease management

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Expression of focal adhesion kinase gene and invasive cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205472

inferred from DOI database lookup

7 January 2021

based on heuristic

Integrin-dependent tyrosine phosphorylation and growth regulation by Vav

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205472

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1205472

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Dimensions Publication ID

28 November 2017

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1 reference