Deregulated DNA polymerase beta strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities (Q43955963)

28 November 2017

Deregulated DNA polymerase beta strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities (English)

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28 November 2017

Mathilde Fréchet

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28 November 2017

Yvan Canitrot

2

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28 November 2017

Anne Bieth

3

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28 November 2017

Eugenia Dogliotti

4

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28 November 2017

Christophe Cazaux

5

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28 November 2017

Jean-Sébastien Hoffmann

6

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28 November 2017

language of work or name

English

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publication date

1 April 2002

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28 November 2017

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28 November 2017

21

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28 November 2017

15

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28 November 2017

2320-2327

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205295

28 November 2017

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cites work

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

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Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents

21 January 2018

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XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

21 January 2018

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Repair synthesis by human cell extracts in cisplatin-damaged DNA is preferentially determined by minor adducts

21 January 2018

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Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

21 January 2018

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Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells.

21 January 2018

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The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

21 January 2018

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Radiation-induced apoptosis: Relevance to radiotherapy

21 January 2018

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Thermodynamics of human DNA ligase I trimerization and association with DNA polymerase beta

21 January 2018

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Single-cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells

21 January 2018

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Initial events in the cellular effects of ionizing radiations: clustered damage in DNA.

21 January 2018

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Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates

21 January 2018

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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

21 January 2018

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21 January 2018

Radiation carcinogenesis

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Significance of multiple mutations in cancer

21 January 2018

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

21 January 2018

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Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction

21 January 2018

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The RAD52 epistasis group in mammalian double strand break repair

21 January 2018

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

21 January 2018

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Differential gene expression in human cancer cells resistant to cisplatin

21 January 2018

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The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit

21 January 2018

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Requirement of mammalian DNA polymerase-beta in base-excision repair.

21 January 2018

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DNA polymerase beta expression differences in selected human tumors and cell lines

21 January 2018

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A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange

21 January 2018

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On the role of DNA double-strand breaks in toxicity and carcinogenesis

21 January 2018

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Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts.

21 January 2018

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A role for p53 in base excision repair.

21 January 2018

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Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response

21 January 2018

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Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells

21 January 2018

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Overexpression of DNA polymerase β: a genomic instability enhancer process.

21 January 2018

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7 January 2021

Delayed Reproductive Death in X-irradiated Chinese Hamster Ovary Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205295

7 January 2021

Incorporation of the guanosine triphosphate analogs 8-oxo-dGTP and 8-NH2-dGTP by reverse transcriptases and mammalian DNA polymerases

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7 January 2021

Somatic mutations at a heterozygous autosomal locus in human cells occur more frequently by allele loss than by intragenic structural alterations

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205295

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Dimensions Publication ID

28 November 2017

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