Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae (Q43906569)

27 November 2017

Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae (English)

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27 November 2017

Streptomyces venezuelae

object named as

Streptomyces venezuelae

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5

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27 November 2017

Yeo Joon Yoon

1

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27 November 2017

Brian J Beck

2

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27 November 2017

Beom Seok Kim

3

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27 November 2017

Han Young Kang

4

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27 November 2017

David H Sherman

6

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27 November 2017

1 February 2002

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27 November 2017

Chemistry and Biology

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27 November 2017

9

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27 November 2017

203-214

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27 November 2017

2

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Manipulation of Modular Polyketide Synthases.

27 November 2017

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Modular organization of genes required for complex polyketide biosynthesis

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Harnessing the Biosynthetic Potential of Modular Polyketide Synthases

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Combinatorial biosynthesis for new drug discovery

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthases

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Alternative modular polyketide synthase expression controls macrolactone structure

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Biosynthesis and combinatorial biosynthesis of pikromycin-related macrolides in Streptomyces venezuelae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Mechanisms of molecular recognition in the pikromycin polyketide synthase

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Biosynthesis of Desosamine: Construction of a New Methymycin/Neomethymycin Analogue by Deletion of a Desosamine Biosynthetic Gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Biosynthesis of Desosamine: Molecular Evidence Suggesting β-Glucosylation as a Self-Resistance Mechanism in Methymycin/Neomethymycin Producing Strain,Streptomyces venezuelae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Biosynthesis of desosamine: construction of a new macrolide carrying a genetically designed sugar moiety

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Engineered intermodular and intramodular polyketide synthase fusions

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

A functional chimeric modular polyketide synthase generated via domain replacement

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Isolation and characterization of 10-deoxymethynolide produced by Streptomyces venezuelae

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator.

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

The Streptomyces plasmid SCP2*: its functional analysis and development into useful cloning vectors.

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900095-9

7 January 2021

10.1016/S1074-5521(02)00095-9

Identifiers

DOI

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27 November 2017

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