Changing the substrate reactivity of 2-hydroxybiphenyl 3-monooxygenase from Pseudomonas azelaica HBP1 by directed evolution. (Q43815822)

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4 December 2019

title

Changing the substrate reactivity of 2-hydroxybiphenyl 3-monooxygenase from Pseudomonas azelaica HBP1 by directed evolution (English)

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4 December 2019

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Willem J.H. van Berkel

7

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4 December 2019

author name string

Andreas Meyer

1

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4 December 2019

Andreas Schmid

2

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4 December 2019

Martin Held

3

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4 December 2019

Adrie H Westphal

4

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4 December 2019

Martina Rothlisberger

5

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4 December 2019

Hans-Peter E Kohler

6

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4 December 2019

Bernard Witholt

8

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4 December 2019

language of work or name

English

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publication date

3 December 2001

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Journal of Biological Chemistry

4 December 2019

published in

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4 December 2019

volume

277

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4 December 2019

issue

7

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4 December 2019

page(s)

5575-5582

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Purification and characterization of 2-hydroxybiphenyl 3-monooxygenase, a novel NADH-dependent, FAD-containing aromatic hydroxylase from Pseudomonas azelaica HBP1.

4 December 2019

cites work

1 reference

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Identification of a novel conserved sequence motif in flavoprotein hydroxylases with a putative dual function in FAD/NAD(P)H binding

21 January 2018

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Catalytic mechanism of 2-hydroxybiphenyl 3-monooxygenase, a flavoprotein from Pseudomonas azelaica HBP1

21 January 2018

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The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression

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Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase

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Metabolism of biphenyl. 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate: the meta-cleavage product from 2,3-dihydroxybiphenyl by Pseudomonas putida

21 January 2018

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Metabolism of 2,2'-dihydroxybiphenyl by Pseudomonas sp. strain HBP1: production and consumption of 2,2',3-trihydroxybiphenyl

21 January 2018

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Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin.

21 January 2018

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Inversion of stereospecificity of vanillyl-alcohol oxidase

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Directed evolution of industrial enzymes

21 January 2018

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Rapid evolution of a protein in vitro by DNA shuffling

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Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents

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Directed evolution of biocatalysts

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Directed evolution of enzyme catalysts

21 January 2018

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Directed evolution of a thermostable esterase.

21 January 2018

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Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine

21 January 2018

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Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

21 January 2018

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On the fidelity of DNA replication: manganese mutagenesis in vitro.

21 January 2018

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Studies of the mechanism of phenol hydroxylase: mutants Tyr289Phe, Asp54Asn, and Arg281Met

21 January 2018

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The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

21 January 2018

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Comparative protein modelling by satisfaction of spatial restraints

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Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase-trimethoprim, a drug-receptor system.

21 January 2018

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21 January 2018

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Recognition of errors in three-dimensional structures of proteins

21 January 2018

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The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis

21 January 2018

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The PHBH fold: Not only flavoenzymes

21 January 2018

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Combinatorial protein design: strategies for screening protein libraries

21 January 2018

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Bioconversions of aliphatic compounds by Pseudomonas oleovorans in multiphase bioreactors: background and economic potential

21 January 2018

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Application of in situ product-removal techniques to biocatalytic processes.

21 January 2018

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The mobile flavin of 4-OH benzoate hydroxylase

21 January 2018

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Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton [...]

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M110018200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11733527%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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