Topoisomerase II poisoning by ICRF-193. (Q43750940)

26 November 2017

Topoisomerase II poisoning by ICRF-193. (English)

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26 November 2017

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ChEBI release 2020-05-28

Huang KC

1

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26 November 2017

Gao H

2

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26 November 2017

Yamasaki EF

3

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26 November 2017

Grabowski DR

4

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26 November 2017

Liu S

5

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26 November 2017

Shen LL

6

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26 November 2017

Chan KK

7

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26 November 2017

Ganapathi R

8

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26 November 2017

Snapka RM

9

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26 November 2017

language of work or name

English

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publication date

27 September 2001

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Journal of Biological Chemistry

26 November 2017

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26 November 2017

276

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26 November 2017

44488-44494

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26 November 2017

48

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Antitumour Activity in a Series of bisDiketopiperazines

26 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M104383200

A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Inverse relationship between catenation and superhelicity in newly replicated simian virus 40 daughter chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

DNA topoisomerase poisons as antitumor drugs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M104383200

Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

XK469, a selective topoisomerase IIbeta poison

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Molecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Roles of NF-kappaB and 26 S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

The termination region for SV40 DNA replication directs the mode of separation for the two sibling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Swiveling and decatenation of replicating simian virus 40 genomes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M104383200

SUMO-1 conjugation to human DNA topoisomerase II isozymes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M104383200

Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

Hypersensitivity of Ku-deficient cells toward the DNA topoisomerase II inhibitor ICRF-193 suggests a novel role for Ku antigen during the G2 and M phases of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104383200

21 January 2018

Identifiers

DOI

10.1074/JBC.M104383200

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26 November 2017

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