P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. (Q43732527)

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English	P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase.	scientific article

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11 November 2019

P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase (English)

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11 November 2019

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ChEBI release 2020-05-28

Brian A. MacVicar

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W Panenka

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H Jijon

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L M Herx

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J N Armstrong

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D Feighan

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T Wei

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V W Yong

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R M Ransohoff

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1 September 2001

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Journal of Neuroscience

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7135-7142

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Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1alpha and monocyte chemotactic protein-1

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https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury.

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https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Basic mechanisms of brain inflammation.

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https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice

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https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Chemotactic activity on mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon-gamma inducible protein-10 and monocyte chemotactic protein-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease

1 reference

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12 December 2020

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Platelet-derived growth factor stimulation of monocyte chemoattractant protein-1 gene expression is mediated by transient activation of the phosphoinositide 3-kinase signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P2 purinoceptors in the immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Rat astroglial P2Z (P2X7) receptors regulate intracellular calcium and purine release

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Modulation of intracellular Ca++ in cultured astrocytes by influx through voltage-activated Ca++ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Endotoxin activation of macrophages does not induce ATP release and autocrine stimulation of P2 nucleotide receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Nucleotides as extracellular signalling molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Receptors for purines and pyrimidines

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Signaling by ATP receptors in astrocytes

1 reference

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12 December 2020

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Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Monocyte chemoattractant protein-1 messenger RNA expression in rat ischemic cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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ATP-stimulated activation of the mitogen-activated protein kinases through ionotrophic P2X2 purinoreceptors in PC12 cells. Difference in purinoreceptor sensitivity in two PC12 cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Activation of p42mapk/erk2 following engagement of tumor necrosis factor receptor CD120a (p55) in mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Monocyte chemoattractant protein (MCP)-1 is rapidly expressed by sympathetic ganglion neurons following axonal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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P2X7 receptors in Müller glial cells from the human retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Nucleotide receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-PDGF receptor induces neuronal differentiation of PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Voltage-activated K+ currents in acutely isolated hippocampal astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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1996 Receptor and ion channel nomenclature supplement

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Attenuation of astroglial reactivity by interleukin-10

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of the enzyme chain hydrolyzing extracellular ATP after transient forebrain ischemia in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overriding the brain's intrinsic resistance to leukocyte recruitment with intraparenchymal injections of recombinant chemokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic-ischemic injury induces monocyte chemoattractant protein-1 expression in neonatal rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of the development of experimental allergic encephalomyelitis by suramin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation of the pore-forming and phospholipase D activities stimulated via P2z purinergic receptors in BAC1.2F5 macrophages. Product inhibition of phospholipase D enzyme activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both Erk and p38 kinases are necessary for cytokine gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Proliferation of astroglia and oligodendroglia in response to human T cell-derived factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

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Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation?

1 reference

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12 December 2020

based on heuristic

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MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein and tyrosine kinases in the activation of astrocyte volume-activated chloride current.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine induction of monocyte chemoattractant protein-1 gene expression in human endothelial cells depends on the cooperative action of NF-kappa B and AP-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential production of MCP-1 and cytokine-induced neutrophil chemoattractant in the ischemic brain after transient focal ischemia in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide receptors in the nervous system. An abundant component using diverse transduction mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ATP4- receptor-operated channel (P2Z class) of human lymphocytes allows Ba2+ and ethidium+ uptake: inhibition of fluxes by suramin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11549724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.21-18-07135.2001

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11 November 2019

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Europe PubMed Central

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11 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11549724%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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