Challenges for the 'chemical-systems' biologist (Q43723540)

26 November 2017

Challenges for the 'chemical-systems' biologist (English)

1 reference

26 November 2017

2

Benjamin F Cravatt

1 reference

26 November 2017

Gabriel M Simon

1

1 reference

26 November 2017

1 November 2008

1 reference

26 November 2017

Nature Chemical Biology

1 reference

26 November 2017

4

1 reference

26 November 2017

11

1 reference

26 November 2017

639-642

1 reference

https://scigraph.springernature.com/pub.10.1038/nchembio1108-639

26 November 2017

0 references

cites work

General nature of the genetic code for proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Exploring the O-GlcNAc proteome: direct identification of O-GlcNAc-modified proteins from the brain

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Direct transfer of extended groups from synthetic cofactors by DNA methyltransferases

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Activity-based protein profiling: from enzyme chemistry to proteomic chemistry

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Chemical approaches for functionally probing the proteome

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

A streamlined platform for high-content functional proteomics of primary human specimens

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Disparate proteome reactivity profiles of carbon electrophiles

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead".

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Activity-based probes for proteomic profiling of histone deacetylase complexes

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

A clickable inhibitor reveals context-dependent autoactivation of p90 RSK

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Mechanistic basis of enzyme-targeted drugs

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Chemical genetics: where genetics and pharmacology meet

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Target identification in chemical genetics: the (often) missing link

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Recognizing and exploiting differences between RNAi and small-molecule inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Sole BCR-ABL inhibition is insufficient to eliminate all myeloproliferative disorder cell populations

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Self-renewal of embryonic stem cells by a small molecule

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Global mapping of the topography and magnitude of proteolytic events in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Mechanism of carbamate inactivation of FAAH: implications for the design of covalent inhibitors and in vivo functional probes for enzymes

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO1108-639

7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO1108-639

1 reference

26 November 2017

1 reference

PubMed ID

18936742