Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia (Q43700513)

26 November 2017

Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia (English)

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26 November 2017

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5

F M Uckun

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26 November 2017

P A Goodman

1

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26 November 2017

C M Wood

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2

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26 November 2017

A Vassilev

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3

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26 November 2017

C Mao

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4

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26 November 2017

language of work or name

English

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publication date

1 July 2001

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26 November 2017

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26 November 2017

20

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26 November 2017

30

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26 November 2017

3969-3978

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204515

26 November 2017

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cites work

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Protein tyrosine kinases in the initiation of antigen receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Leukocyte protein tyrosine kinases: potential targets for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Regulation of antigen receptor signal transduction by protein tyrosine kinases

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Interaction of phosphorylated FcepsilonRIgamma immunoglobulin receptor tyrosine activation motif-based peptides with dual and single SH2 domains of p72syk. Assessment of binding parameters and real time binding kinetics

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Syk tyrosine kinase required for mouse viability and B-cell development

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

A unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Syk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mitogen-activated protein kinase-independent pathway in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Signalling in lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

A deficiency in Syk enhances ceramide-induced apoptosis in DT40 lymphoma B cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Treatment outcome and prognostic factors for infants with acute lymphoblastic leukemia treated on two consecutive trials of the Children's Cancer Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Molecular cloning of rodent p72Syk. Evidence of alternative mRNA splicing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Human spleen tyrosine kinase p72Syk associates with the Src-family kinase p53/56Lyn and a 120-kDa phosphoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Prognostic significance of the CD10+CD19+CD34+ B-progenitor immunophenotype in children with acute lymphoblastic leukemia: a report from the Children's Cancer Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Physical and functional interactions between Lyn and p34cdc2 kinases in irradiated human B-cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Cloning of the cDNA for the deleted syk kinase homologous to ZAP-70 from human basophilic leukemia cell line (KU812).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

7 January 2021

Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

7 January 2021

Tyrosine phosphorylation of Shc is mediated through Lyn and Syk in B cell receptor signaling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

7 January 2021

Zapping T-cell responses

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

7 January 2021

Clinical significance of translocation t(1;19) in childhood acute lymphoblastic leukemia in the context of contemporary therapies: a report from the Children's Cancer Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204515

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204515

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Dimensions Publication ID

26 November 2017

1035499551

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Fatcat ID

release_uu5vpwel7fhtfkiqyo6swlpasy

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Fatcat

https://api.fatcat.wiki/v0/release/uu5vpwel7fhtfkiqyo6swlpasy

24 November 2022

mapped directly with Wikidata item

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