Characterization of biotransformation enzyme activities in primary rat proximal tubular cells (Q43580779)

24 November 2017

Characterization of biotransformation enzyme activities in primary rat proximal tubular cells (English)

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24 November 2017

Schaaf GJ

1

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24 November 2017

de Groene EM

2

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24 November 2017

Maas RF

3

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24 November 2017

Commandeur JN

4

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24 November 2017

Fink-Gremmels J

5

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24 November 2017

1 April 2001

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Chemico-biological Interactions

24 November 2017

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24 November 2017

134

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24 November 2017

2

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24 November 2017

167-190

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Molecular and biochemical mechanisms of chemically induced nephrotoxicity: a review.

24 November 2017

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https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Isolated proximal tubular cells from rat kidney as an in vitro model for studies on nephrotoxicity. I. An improved method for preparation of proximal tubular cells and their functional characterization by alpha-methylglucose uptake

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Biotransformation and membrane transport in nephrotoxicity

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Metabolism of drugs by the kidney

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Induction of drug-metabolizing enzymes by xenobiotics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Role of cytochrome P450 and glutathione S-transferase alpha in the metabolism and cytotoxicity of trichloroethylene in rat kidney.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Susceptibility of primary cultures of proximal tubular and distal tubular cells from rat kidney to chemically induced toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and in intact monolayers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Assay of apical membrane enzymes based on fluorogenic substrates

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Effects of cooked brussels sprouts on cytochrome P-450 profile and phase II enzymes in liver and small intestinal mucosa of the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Characterization of primary rabbit kidney cultures that express proximal tubule functions in a hormonally defined medium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Cytochrome P4502C11 is a target of diclofenac covalent binding in rats

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

In vitro systems for nephrotoxicity studies.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Interspecies variations in caffeine metabolism related to cytochrome P4501A enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Caffeine urinary metabolite ratios as markers of enzyme activity: a theoretical assessment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine; identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patt

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Primary and secondary oxidative metabolism of dextromethorphan

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Gliclazide hydroxylation by rat liver microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Tissue distributions of CYP2D1, 2D2, 2D3 and 2D4 mRNA in rats detected by RT-PCR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Regional and cellular distribution of CYP2D subfamily members in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Phase I and phase II xenobiotic biotransformation in cultures and co-cultures of adult rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Rat adult hepatocytes in primary pure and mixed monolayer culture. Comparison of the maintenance of mixed function oxidase and conjugation pathways of drug metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Problems in using isolated and cultured hepatocytes for xenobiotic metabolism/metabolism-based toxicity testing-Solutions?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Altered expression of cytochrome P-450 mRNAs, and potentially of other transcripts encoding key hepatic functions, are triggered during the isolation of rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

Analysis of cytochrome P450 and phase II conjugating enzyme expression in adult male rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

3-D coculture of hepatic sinusoidal cells with primary hepatocytes-design of an organotypical model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900151-X

10.1016/S0009-2797(01)00151-X

7 January 2021

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DOI

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24 November 2017

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