Cholesterol reduction attenuates 5-HT1A receptor-mediated signaling in human primary neuronal cultures. (Q43573099)

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10 January 2020

title

Cholesterol reduction attenuates 5-HT1A receptor-mediated signaling in human primary neuronal cultures (English)

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10 January 2020

1

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10 January 2020

author name string

Linda Csöregh

series ordinal

2

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10 January 2020

Per Svenningsson

series ordinal

3

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publication date

8 July 2008

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Naunyn-Schmiedeberg's Archives of Pharmacology

10 January 2020

published in

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volume

378

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issue

4

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10 January 2020

page(s)

441-446

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https://scigraph.springernature.com/pub.10.1007/s00210-008-0323-6

10 January 2020

exact match

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cites work

Segregation of heterotrimeric G proteins in cell surface microdomains. G(q) binds caveolin to concentrate in caveolae, whereas G(i) and G(s) target lipid rafts by default

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Coupling of 5-HT1A autoreceptors to inhibition of mitogen-activated protein kinase activation via G beta gamma subunit signaling.

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The evolving role of lipid rafts and caveolae in G protein-coupled receptor signaling: implications for molecular pharmacology

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Cholesterol depletion induces dynamic confinement of the G-protein coupled serotonin(1A) receptor in the plasma membrane of living cells.

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Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway

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5-HT1A receptor immunoreactivity in hypothalamic neurons involved in body weight control

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The G protein-coupled 5-HT1A receptor causes suppression of caspase-3 through MAPK and protein kinase Calpha

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Molecular, pharmacological and functional diversity of 5-HT receptors

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G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there?

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Cholesterol modulates the antagonist-binding function of hippocampal serotonin1A receptors

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Localization of the mouse 5-hydroxytryptamine(1A) receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling.

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Ras-dependent activation of fibroblast mitogen-activated protein kinase by 5-HT1A receptor via a G protein beta gamma-subunit-initiated pathway.

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Agonist properties of pindolol at h5-HT1A receptors coupled to mitogen-activated protein kinase

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Species differences in regional patterns of 3H-8-OH-DPAT and 3H-zolpidem binding in the rat and human brain.

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A review of central 5-HT receptors and their function

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Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated with Major Depression and Suicide

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Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors

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12 December 2020

Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors

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Neurons and glial cells of the embryonic human brain and spinal cord express multiple and distinct isoforms of laminin.

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5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain

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Estrogen receptor beta is expressed in human embryonic brain cells and is regulated by 17beta-estradiol

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Lipid rafts and signal transduction

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Cholesterol modulates ligand binding and G-protein coupling to serotonin(1A) receptors from bovine hippocampus.

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Desensitization of 5-HT1A receptors by 5-HT2A receptors in neuroendocrine neurons in vivo.

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12 December 2020

Depletion of the lipid raft constituents, sphingomyelin and ganglioside, decreases serotonin binding at human 5-HT7(a)receptors in HeLa cells

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12 December 2020

10.1007/S00210-008-0323-6

Identifiers

DOI

1 reference

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10 January 2020

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