Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity (Q43557673)

24 November 2017

Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity (English)

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24 November 2017

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Pérez MJ

1

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PubMed ID

11275473

24 November 2017

Cederbaum AI

series ordinal

2

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PubMed ID

11275473

24 November 2017

language of work or name

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1 April 2001

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Free Radical Biology and Medicine

24 November 2017

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24 November 2017

30

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24 November 2017

7

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24 November 2017

734-746

1 reference

Implication of free radical mechanisms in ethanol-induced cellular injury

24 November 2017

1 reference

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7 January 2021

Role of lipid peroxidation and oxidative stress in alcohol toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Increased NADPH- and NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Stable expression of human cytochrome P4502E1 in HepG2 cells: characterization of catalytic activities and production of reactive oxygen intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)

1 reference

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7 January 2021

Hydroxyethyl radicals in ethanol hepatotoxicity

1 reference

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7 January 2021

Possible roles of free radicals in alcoholic tissue damage

1 reference

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7 January 2021

Biochemistry of alcoholic liver disease

1 reference

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7 January 2021

Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol-inducible cytochrome P450 (CYP2E1) in the liver of rats chronically fed ethanol

1 reference

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7 January 2021

Changes in Microsomal Phospholipases and Arachidonic Acid in Experimental Alcoholic Liver Injury: Relationship to Cytochrome P-450 2E1 Induction and Conjugated Diene Formation

1 reference

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7 January 2021

Role of cytochrome P4502E1 in alcoholic liver disease pathogenesis

1 reference

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7 January 2021

Relationship between pork consumption and cirrhosis

1 reference

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7 January 2021

Dietary factors and alcoholic cirrhosis

1 reference

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7 January 2021

Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1.

1 reference

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7 January 2021

Oxidative stress and cytotoxicity induced by ferric-nitrilotriacetate in HepG2 cells that express cytochrome P450 2E1.

1 reference

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7 January 2021

MPTP-induced deficits in motor activity: neuroprotective effects of the spintrapping agent, alpha-phenyl-tert-butyl-nitrone (PBN)

1 reference

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7 January 2021

The free radical spin trap alpha-phenyl-tert-butyl nitrone attenuates the cerebral response to deep hypothermic ischemia

1 reference

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7 January 2021

Role of oxidative stress and the glutathione system in loss of dopamine neurons due to impairment of energy metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Tempol reduces infarct size in rodent models of regional myocardial ischemia and reperfusion

1 reference

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7 January 2021

Protective effects of spin-trapping agents on adriamycin-induced cardiotoxicity in isolated rat atria

1 reference

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7 January 2021

Pharmacological protection of NSAID-induced intestinal permeability in the rat: effect of tempo and metronidazole as potential free radical scavengers

1 reference

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7 January 2021

A stable nitroxide radical effectively decreases mucosal damage in experimental colitis

1 reference

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7 January 2021

Protection against aminoglycoside otic drop-induced ototoxicity by a spin trap: I. Acute effects

1 reference

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7 January 2021

The Protective Effects of Tirilated Mesylate (U74006F) on Ischemic and Reperfusion-Induced Cochlear Damage

1 reference

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7 January 2021

The protective effects of allopurinol and superoxide dismutase on noise-induced cochlear damage.

1 reference

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7 January 2021

Two-week administration of tempol attenuates both hypertension and renal excretion of 8-Iso prostaglandin f2alpha

1 reference

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7 January 2021

Evaluation of nitrone spin-trapping agents as radioprotectors

1 reference

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7 January 2021

Pretreatment with polynitroxyl albumin (PNA) inhibits ischemia-reperfusion induced leukocyte-endothelial cell adhesion.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Both hydroxylamine and nitroxide protect cardiomyocytes from oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Stable nitroxide radicals protect lipid acyl chains from radiation damage

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.

1 reference

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7 January 2021

Protease activation during apoptosis: death by a thousand cuts?

1 reference

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7 January 2021

The last cut is the deepest

1 reference

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7 January 2021

Loss of function of cytochrome c in Jurkat cells undergoing fas-mediated apoptosis

1 reference

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7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

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7 January 2021

Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome

1 reference

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7 January 2021

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

1 reference

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7 January 2021

A role for metals and free radicals in the induction of apoptosis in thymocytes

1 reference

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7 January 2021

Sites and mechanisms of low-level oxidative stress in cultured cells

1 reference

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7 January 2021

Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis

1 reference

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7 January 2021

The thiol-specific antioxidant enzyme prevents mitochondrial permeability transition. Evidence for the participation of reactive oxygen species in this mechanism

1 reference

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7 January 2021

Manganese superoxide dismutase modulates interleukin-1alpha levels in HT-1080 fibrosarcoma cells.

1 reference

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7 January 2021

Do spin traps also act as classical chain-breaking antioxidants? A quantitative kinetic study of phenyl tert-butylnitrone (PBN) in solution and in liposomes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Metabolism of ethanol to 1-hydroxyethyl radicals in rat liver microsomes: comparative studies with three spin trapping agents

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Cell fatty acid composition affects free radical formation during lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Metabolism in rat liver microsomes of the nitroxide spin probe tempol.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Cardiac reperfusion damage prevented by a nitroxide free radical

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Decline in the expression of copper/zinc superoxide dismutase in the kidney of rats with endotoxic shock: effects of the superoxide anion radical scavenger, tempol, on organ injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Do nitroxide antioxidants act as scavengers of O2-. or as SOD mimics?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Nitroxide stable radicals protect beating cardiomyocytes against oxidative damage

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Microassay of superoxide anion scavenging activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Protective effect of the nitroxide tempol against the cardiotoxicity of adriamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Biologically active metal-independent superoxide dismutase mimics

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Nitroxide radicals protect DNA from damage when illuminated in vitro in the presence of dibenzoylmethane and a common sunscreen ingredient.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Tempol inhibits neutrophil and hydrogen peroxide-mediated DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

Complete suppresion of ethanol-induced formation of megamitochondria by 4-hydroxy-2,2,6,6-tetramethyl-piperidine-1-oxyl (4-OH-TEMPO)

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2801%2900461-0

7 January 2021

10.1016/S0891-5849(01)00461-0

Identifiers

DOI

1 reference

24 November 2017

1 reference

PubMed ID

11275473