Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation (Q43511052)

24 November 2017

Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation (English)

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24 November 2017

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Qin ZH

1

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24 November 2017

Wang Y

2

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24 November 2017

Kikly KK

3

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24 November 2017

Sapp E

4

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24 November 2017

Kegel KB

5

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24 November 2017

Aronin N

6

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24 November 2017

DiFiglia M

7

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24 November 2017

language of work or name

English

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publication date

1 December 2000

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

8079-8086

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24 November 2017

11

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

24 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Multiple pathways to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Life and death of neurons in the aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Mammalian cell death proteases: a family of highly conserved aspartate specific cysteine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

The mitochondrial death/life regulator in apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Caspases: intracellular signaling by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Dismantling in cell death: molecular mechanisms and relationship to caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Synthesis of mixed ferrite with spinel-type structure from a stainless steelmaking solid waste

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Apoptosis by death factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Tumor necrosis factor receptor and Fas signaling mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Pro-caspase-3 is a major physiologic target of caspase-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

The mitochondrial permeability transition pore and its role in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Mitochondrial control of cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007028200

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Cytochrome c: can't live with it--can't live without it.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Mitochondria and apoptosis: HQ or high-security prison?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Mitochondrial release of caspase-2 and -9 during the apoptotic process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Detection of pro-caspase-3 in cytosol and mitochondria of various tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Mitochondrial heat shock protein 70 is distributed throughout the mitochondrion in a dyskinetoplastic mutant of Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Caspase activation: the induced-proximity model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

An induced proximity model for caspase-8 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Caspases: their intracellular localization and translocation during apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

The death domain: a module shared by proteins with diverse cellular functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Subcellular localization and CARD-dependent oligomerization of the death adaptor RAIDD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

A1 functions at the mitochondria to delay endothelial apoptosis in response to tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in Fas-mediated hepatic apoptosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Mitochondrial dysfunction in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007028200

21 January 2018

Identifiers

DOI

10.1074/JBC.M007028200

1 reference

24 November 2017

1 reference