Phosphatidic acid and diacylglycerol directly activate NADPH oxidase by interacting with enzyme components (Q43509184)

24 November 2017

Phosphatidic acid and diacylglycerol directly activate NADPH oxidase by interacting with enzyme components (English)

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24 November 2017

A Palicz

1

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24 November 2017

T R Foubert

2

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24 November 2017

A J Jesaitis

3

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24 November 2017

L Marodi

4

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24 November 2017

L C McPhail

5

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24 November 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

5

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24 November 2017

3090-3097

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Genetic, biochemical, and clinical features of chronic granulomatous disease.

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Activation of the leukocyte NADPH oxidase by protein kinase C in a partially recombinant cell-free system.

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Essential requirement of cytosolic phospholipase A2 for activation of the phagocyte NADPH oxidase.

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A novel protein kinase target for the lipid second messenger phosphatidic acid

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Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages

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Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system

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Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid

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Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase.

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Conformational changes of the leukocyte NADPH oxidase subunit p47(phox) during activation studied through its intrinsic fluorescence

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Electron transfer across the O2- generating flavocytochrome b of neutrophils. Evidence for a transition from a low-spin state to a high-spin state of the heme iron component.

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Cell-free activation of neutrophil NADPH oxidase by a phosphatidic acid-regulated protein kinase

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Phosphatidic acid-mediated phosphorylation of the NADPH oxidase component p47-phox. Evidence that phosphatidic acid may activate a novel protein kinase.

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Interleukin-2 causes an increase in saturated/monounsaturated phosphatidic acid derived from 1,2-diacylglycerol and 1-O-alkyl-2-acylglycerol

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Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes

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Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms

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Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000

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Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation

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Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase

21 January 2018

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Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

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Activation of the phagocyte NADPH oxidase protein p47(phox). Phosphorylation controls SH3 domain-dependent binding to p22(phox).

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How cytidylyltransferase uses an amphipathic helix to sense membrane phospholipid composition

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Diacylglycerol kinase inhibitors R59022 and dioctanoylethylene glycol potentiate the respiratory burst of neutrophils by raising cytosolic Ca2+

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Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids

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Molecular and biochemical characterization of a recombinant human PKC-delta family member

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Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells

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21 January 2018

Identifiers

DOI

10.1074/JBC.M007759200

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24 November 2017

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