Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. (Q43508981)

24 November 2017

Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. (English)

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24 November 2017

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5

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24 November 2017

Yamaguchi A

1

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24 November 2017

Tamatani M

2

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24 November 2017

Matsuzaki H

3

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24 November 2017

Namikawa K

4

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24 November 2017

Vitek MP

6

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24 November 2017

Mitsuda N

7

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24 November 2017

Tohyama M

8

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24 November 2017

language of work or name

English

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publication date

27 October 2000

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

5256-5264

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24 November 2017

7

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The p53 pathway and apoptosis

24 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium. Increased monolayer permeability and induction of procoagulant properties

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Efficient selection for high-expression transfectants with a novel eukaryotic vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Definition of a consensus binding site for p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M008552200

Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

p53 regulation by post-translational modification and nuclear retention in response to diverse stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008552200

21 January 2018

Identifiers

DOI

10.1074/JBC.M008552200

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release_46jpqcgxlrgvvaj5bkmpnmslx4

24 November 2017

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Fatcat

https://api.fatcat.wiki/v0/release/46jpqcgxlrgvvaj5bkmpnmslx4

mapped directly with Wikidata item

24 November 2022

based on heuristic

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