Shigella sonnei vaccine candidates WRSs2 and WRSs3 are as immunogenic as WRSS1, a clinically tested vaccine candidate, in a primate model of infection. (Q43432983)

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scientific article published on 17 May 2011

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English	Shigella sonnei vaccine candidates WRSs2 and WRSs3 are as immunogenic as WRSS1, a clinically tested vaccine candidate, in a primate model of infection.	scientific article published on 17 May 2011

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1 February 2020

Shigella sonnei vaccine candidates WRSs2 and WRSs3 are as immunogenic as WRSS1, a clinically tested vaccine candidate, in a primate model of infection (English)

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Shigella sonnei

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Shigella sonnei

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Robert W Kaminski

3

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S Barnoy

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S Baqar

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T Collins

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K Nemelka

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T L Hale

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R T Ranallo

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M M Venkatesan

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17 May 2011

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6371-6378

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Host-bacteria homeostasis in the healthy and inflamed gut.

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Effect of prior infection with virulent Shigella flexneri 2a on the resistance of monkeys to subsequent infection with Shigella sonnei

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OmpB (osmo-regulation) and icsA (cell-to-cell spread) mutants of Shigella flexneri: vaccine candidates and probes to study the pathogenesis of shigellosis

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Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colon

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The bacterial weaponry: lessons from Shigella

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Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement

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Molecular basis of the intracellular spreading of Shigella

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Intracellular survival of Shigella

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Cadherin expression is required for the spread of Shigella flexneri between epithelial cells

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icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread

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IcsB, secreted via the type III secretion system, is chaperoned by IpgA and required at the post-invasion stage of Shigella pathogenicity

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Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin

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The unipolar Shigella surface protein IcsA is targeted directly to the bacterial old pole: IcsP cleavage of IcsA occurs over the entire bacterial surface

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Construction and characterization of virG (icsA)-deleted Escherichia coli K12-Shigella flexneri hybrid vaccine strains.

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Construction, characterization, and animal testing of WRSd1, a Shigella dysenteriae 1 vaccine

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Immunogenicity and characterization of WRSF2G11: a second generation live attenuated Shigella flexneri 2a vaccine strain.

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Phase I evaluation of delta virG Shigella sonnei live, attenuated, oral vaccine strain WRSS1 in healthy adults

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Two studies evaluating the safety and immunogenicity of a live, attenuated Shigella flexneri 2a vaccine (SC602) and excretion of vaccine organisms in North American volunteers.

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Community-based safety, immunogenicity, and transmissibility study of the Shigella sonnei WRSS1 vaccine in Israeli volunteers

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Safety and immunogenicity of WRSd1, a live attenuated Shigella dysenteriae type 1 vaccine candidate.

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Characterization of WRSs2 and WRSs3, new second-generation virG(icsA)-based Shigella sonnei vaccine candidates with the potential for reduced reactogenicity

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Enteric infections in chimpanzees and spider monkeys with special reference to a sulfadiazine resistant Shigella.

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Potentials of Shigella flexneri Y strain TSF21 as a candidate vaccine against shigellosis: safety, immunogenicity and protective efficacy in Bonnet monkeys.

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AroD deletion attenuates Shigella flexneri strain 2457T and makes it a safe and efficacious oral vaccine in monkeys

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Safety, immunogenicity, and efficacy in monkeys and humans of invasive Escherichia coli K-12 hybrid vaccine candidates expressing Shigella flexneri 2a somatic antigen.

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Fluorescent-Antibody and Histological Study of Vaccinated and Control Monkeys Challenged with Shigella flexneri

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Prospective study of systemic and mucosal immune responses in dysenteric patients to specific Shigella invasion plasmid antigens and lipopolysaccharides.

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