MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa (Q43280141)

18 November 2017

MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa (English)

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18 November 2017

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18 November 2017

Nicholas J Hawkins

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author name string

James H-F Lee

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18 November 2017

Justin J-L Wong

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18 November 2017

Chau-To Kwok

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18 November 2017

Megan P Hitchins

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18 November 2017

4 September 2009

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22

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1588-1599

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https://scigraph.springernature.com/pub.10.1038/modpathol.2009.130

18 November 2017

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cites work

Potential predictive markers of response to EGFR-targeted therapies in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

Oncologists' current opinion on the treatment of colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

CpG island methylation in aberrant crypt foci of the colorectum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

Cloning and analysis of the murine Foxi2 transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

The epigenomics of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

CpG island methylator phenotype in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

MGMT promoter methylation and field defect in sporadic colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

MGMT: its role in cancer aetiology and cancer therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

O(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitions

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Lomeguatrib, a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase: phase I safety, pharmacodynamic, and pharmacokinetic trial and evaluation in combination with temozolomide in patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Serrated adenoma of the colorectum and the DNA-methylator phenotype

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

CpG island methylation is frequently present in tubulovillous and villous adenomas and correlates with size, site, and villous component.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Identification of a 59 bp enhancer located at the first exon/intron boundary of the human O6-methylguanine DNA methyltransferase gene

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Microsatellite instability and the clinicopathological features of sporadic colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

MethyLight: a high-throughput assay to measure DNA methylation

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

DNA methylation analysis by MethyLight technology

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Cytoplasmic sequestration of an O6-methylguanine-DNA methyltransferase enhancer binding protein in DNA repair-deficient human cells

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

Genetic and epigenetic profiling in early colorectal tumors and prediction of invasive potential in pT1 (early invasive) colorectal cancers.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2009.130

7 January 2021

10.1038/MODPATHOL.2009.130

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18 November 2017

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