A chimeric LDL receptor containing the cytoplasmic domain of the transferrin receptor is degraded by PCSK9. (Q43261493)

17 November 2017

A chimeric LDL receptor containing the cytoplasmic domain of the transferrin receptor is degraded by PCSK9. (English)

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17 November 2017

Øystein L Holla

1

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17 November 2017

Thea Bismo Strøm

2

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17 November 2017

Jamie Cameron

3

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17 November 2017

Knut Erik Berge

4

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17 November 2017

Trond P Leren

5

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17 November 2017

27 September 2009

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Molecular Genetics and Metabolism

17 November 2017

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17 November 2017

99

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17 November 2017

2

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17 November 2017

149-156

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

17 November 2017

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements

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Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

7 January 2021

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MIR is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth

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LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor

7 January 2021

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The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Mutations and polymorphisms in the proprotein convertase subtilisin kexin 9 (PCSK9) gene in cholesterol metabolism and disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Degradation of the LDL receptors by PCSK9 is not mediated by a secreted protein acted upon by PCSK9 extracellularly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Retention of mutant low density lipoprotein receptor in endoplasmic reticulum (ER) leads to ER stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Model system for phenotypic characterization of sequence variations in the LDL receptor gene

7 January 2021

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4-Phenylbutyrate restores the functionality of a misfolded mutant low-density lipoprotein receptor.

7 January 2021

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Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy

7 January 2021

1 reference

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The amino terminus of GLUT4 functions as an internalization motif but not an intracellular retention signal when substituted for the transferrin receptor cytoplasmic domain

7 January 2021

1 reference

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The LOX-1 scavenger receptor cytoplasmic domain contains a transplantable endocytic motif

7 January 2021

1 reference

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The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation

7 January 2021

1 reference

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Signal-dependent membrane protein trafficking in the endocytic pathway

7 January 2021

1 reference

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Regulation of receptors and transporters by ubiquitination: new insights into surprisingly similar mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

Degradation of LDLR protein mediated by 'gain of function' PCSK9 mutants in normal and ARH cells

7 January 2021

1 reference

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Pathways and mechanisms of endocytic recycling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.09.012

10.1016/J.YMGME.2009.09.012

7 January 2021

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DOI

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17 November 2017

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