UNC-87, a calponin-related protein in C. elegans, antagonizes ADF/cofilin-mediated actin filament dynamics. (Q43204257)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

UNC-87, a calponin-related protein in C. elegans, antagonizes ADF/cofilin-mediated actin filament dynamics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

main subject

Caenorhabditis elegans

0 references

actin filament

1 reference

Protein unc-87 CELE_F08B6.4

inferred from title

1 reference

GOA release 2020-03-11

author

Shoichiro Ono

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Sawako Yamashiro

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Mario Gimona

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

language of work or name

English

0 references

publication date

7 August 2007

1 reference

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3 January 2020

published in

Journal of Cell Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

120

1 reference

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3 January 2020

issue

Pt 17

1 reference

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3 January 2020

page(s)

3022-3033

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers.

3 January 2020

cites work

1 reference

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Mechanism of depolymerization and severing of actin filaments and its significance in cytoskeletal dynamics.

25 May 2018

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Spatial and temporal relationships between actin-filament nucleation, capping, and disassembly

25 May 2018

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Novel structures for alpha-actinin:F-actin interactions and their implications for actin-membrane attachment and tension sensing in the cytoskeleton

25 May 2018

1 reference

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Actin filament severing by cofilin

25 May 2018

1 reference

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Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis

25 May 2018

1 reference

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Targeted Deletion of the Muscular Dystrophy Gene myotilin Does Not Perturb Muscle Structure or Function in Mice

25 May 2018

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The ARP2/3 complex: an actin nucleator comes of age

25 May 2018

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25 May 2018

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Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo

25 May 2018

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Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle

25 May 2018

1 reference

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The CH-domain of calponin does not determine the modes of calponin binding to F-actin

25 May 2018

1 reference

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Caenorhabditis elegans kettin, a large immunoglobulin-like repeat protein, binds to filamentous actin and provides mechanical stability to the contractile apparatuses in body wall muscle

25 May 2018

1 reference

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Cofilin cross-bridges adjacent actin protomers and replaces part of the longitudinal F-actin interface.

25 May 2018

1 reference

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Enhancement of actin-depolymerizing factor/cofilin-dependent actin disassembly by actin-interacting protein 1 is required for organized actin filament assembly in the Caenorhabditis elegans body wall muscle

25 May 2018

1 reference

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Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration

25 May 2018

1 reference

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Nebulin regulates the assembly and lengths of the thin filaments in striated muscle

25 May 2018

1 reference

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Tropomyosin isoforms: divining rods for actin cytoskeleton function

25 May 2018

1 reference

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Formin proteins: a domain-based approach.

25 May 2018

1 reference

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Myosin-II-dependent localization and dynamics of F-actin during cytokinesis

25 May 2018

1 reference

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Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin

25 May 2018

1 reference

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Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells

25 May 2018

1 reference

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Congenital myopathies: diseases of the actin cytoskeleton.

25 May 2018

1 reference

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Xin repeats define a novel actin-binding motif.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Cofilin promotes actin polymerization and defines the direction of cell motility

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

The role of calponin in the gene profile of metastatic cells: inhibition of metastatic cell motility by multiple calponin repeats

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton

25 May 2018

1 reference

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Calponin repeats regulate actin filament stability and formation of podosomes in smooth muscle cells

25 May 2018

1 reference

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Cellular motility driven by assembly and disassembly of actin filaments

25 May 2018

1 reference

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Myotilin, the limb-girdle muscular dystrophy 1A (LGMD1A) protein, cross-links actin filaments and controls sarcomere assembly

25 May 2018

1 reference

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Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge

25 May 2018

1 reference

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Functional plasticity of CH domains.

25 May 2018

1 reference

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Tropomyosin inhibits ADF/cofilin-dependent actin filament dynamics

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Actin depolymerizing factor stabilizes an existing state of F-actin and can change the tilt of F-actin subunits

25 May 2018

1 reference

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The Caenorhabditis elegans unc-78 gene encodes a homologue of actin-interacting protein 1 required for organized assembly of muscle actin filaments

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

UNC-87 is an actin-bundling protein

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

The C-terminal tail of UNC-60B (actin depolymerizing factor/cofilin) is critical for maintaining its stable association with F-actin and is implicated in the second actin-binding site.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Live dynamics of GFP-calponin: isoform-specific modulation of the actin cytoskeleton and autoregulation by C-terminal sequences

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Actin filaments are severed by both native and recombinant dictyostelium cofilin but to different extents

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

UNC-60B, an ADF/cofilin family protein, is required for proper assembly of actin into myofibrils in Caenorhabditis elegans body wall muscle

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

The single CH domain of calponin is neither sufficient nor necessary for F-actin binding

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Cofilin changes the twist of F-actin: implications for actin filament dynamics and cellular function

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Cofilin promotes rapid actin filament turnover in vivo

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Genetic organization of the unc-60 region in Caenorhabditis elegans

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

The Caenorhabditis elegans muscle-affecting gene unc-87 encodes a novel thin filament-associated protein

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

The Caenorhabditis elegans UNC-87 protein is essential for maintenance, but not assembly, of bodywall muscle

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Tropomyosin binding to F-actin protects the F-actin from disassembly by brain actin-depolymerizing factor (ADF).

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

The unc-86 gene product couples cell lineage and cell identity in C. elegans

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

The actin filament severing protein actophorin promotes the formation of rigid bundles of actin filaments crosslinked with alpha-actinin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Characterization of actin filament severing by actophorin from Acanthamoeba castellanii

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Structural and mechanical basis of exercise-induced muscle injury

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Mechanism of actin filament turnover by severing and nucleation at different concentrations of ADF/cofilin.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Myotilinopathy: refining the clinical and myopathological phenotype

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Cortical actin turnover during cytokinesis requires myosin II.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Actin filament disassembling activity of Caenorhabditis elegans actin-interacting protein 1 (UNC-78) is dependent on filament binding by a specific ADF/cofilin isoform

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Specific requirement for two ADF/cofilin isoforms in distinct actin-dependent processes in Caenorhabditis elegans.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Actin dynamics at pointed ends regulates thin filament length in striated muscle

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Formation of sarcomeres in developing myotubes: role of mechanical stretch and contractile activation.

15 August 2018

1 reference

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Purification and biochemical characterization of actin from Caenorhabditis elegans: its difference from rabbit muscle actin in the interaction with nematode ADF/cofilin

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

F-actin-binding proteins.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Genome structure, mapping and expression of the tropomyosin gene tmy-1 of Caenorhabditis elegans.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2365702

Actin dynamics: tropomyosin provides stability

15 August 2018

1 reference

12 December 2020

Microscopic evidence that actin-interacting protein 1 actively disassembles actin-depolymerizing factor/Cofilin-bound actin filaments

1 reference

12 December 2020

Purification of muscle actin

1 reference

12 December 2020

Actophorin preferentially binds monomeric ADP-actin over ATP-bound actin: consequences for cell locomotion

1 reference

12 December 2020

Two Caenorhabditis elegans actin depolymerizing factor/cofilin proteins, encoded by the unc-60 gene, differentially regulate actin filament dynamics

1 reference

12 December 2020

The effect of two actin depolymerizing factors (ADF/cofilins) on actin filament turnover : pH sensitivity of F-actin binding by human ADF, but not of Acanthamoeba actophorin

1 reference

12 December 2020

Effects of BTS (N-benzyl-p-toluene sulphonamide), an inhibitor for myosin-actin interaction, on myofibrillogenesis in skeletal muscle cells in culture

1 reference

12 December 2020

Interaction of elongation factor 1alpha from Zea mays (ZmEF-1alpha) with F-actin and interplay with the maize actin severing protein, ZmADF3

1 reference

12 December 2020

Identifiers

DOI

10.1242/JCS.013516

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684058%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference