Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice (Q43193940)

15 November 2017

Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice (English)

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15 November 2017

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Kristen A Lantz

1

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15 November 2017

Susan G Emeigh Hart

2

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15 November 2017

Sonia L Planey

3

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15 November 2017

Mitchell F Roitman

4

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15 November 2017

Inez A Ruiz-White

5

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15 November 2017

Henry R Wolfe

6

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15 November 2017

Michael P McLane

7

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15 November 2017

14 January 2010

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15 November 2017

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15 November 2017

18

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15 November 2017

1516-1523

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Protein-tyrosine phosphatase 1B (PTP1B): a novel therapeutic target for type 2 diabetes mellitus, obesity and related states of insulin resistance

15 November 2017

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Targeted and extended acetylation of histones H4 and H3 at active and inactive genes in chicken embryo erythrocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2009.444

Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Increased abundance of specific skeletal muscle protein-tyrosine phosphatases in a genetic model of insulin-resistant obesity and diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

PTP1B regulates leptin signal transduction in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Neuronal PTP1B regulates body weight, adiposity and leptin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Insulin signaling in the central nervous system: a critical role in metabolic homeostasis and disease from C. elegans to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Intracellular signalling. Key enzyme in leptin-induced anorexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Reduction of hypothalamic protein tyrosine phosphatase improves insulin and leptin resistance in diet-induced obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Appetite suppression and weight reduction by a centrally active aminosterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

A novel aminosterol reverses diabetes and fatty liver disease in obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Associative learning mediates dynamic shifts in dopamine signaling in the nucleus accumbens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Changes in energy expenditure resulting from altered body weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

High circulating thyrotropin levels in obese women are reduced after body weight loss induced by caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Protein tyrosine phosphatase 1B interacts with the activated insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Structural and evolutionary relationships among protein tyrosine phosphatase domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

The comparative physiology of food deprivation: from feast to famine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

The neuroendocrinology of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Protein-tyrosine phosphatase 1B as a potential drug target for obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

PTP1B: from the sidelines to the front lines!

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Inhibition of protein tyrosine phosphatase 1B as a potential treatment of diabetes and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

Blood corticosterone concentration reaches critical illness levels early during acute malnutrition in the weanling mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

inferred from DOI database lookup

7 January 2021

based on heuristic

Protein tyrosine phosphatase 1B interacts with the activated insulin receptor

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2009.444

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/OBY.2009.444

1 reference

15 November 2017

1 reference