Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity (Q43079790)

13 November 2017

Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity (English)

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13 November 2017

1

1 reference

13 November 2017

Jon M Laurent

2

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Austin G Meyer

object named as

Austin G Meyer

series ordinal

4

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Claus O. Wilke

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5

object named as

Claus O Wilke

1 reference

13 November 2017

Christopher M Yellman

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3

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PMCID

4718922

13 November 2017

language of work or name

English

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publication date

1 May 2015

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13 November 2017

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13 November 2017

348

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13 November 2017

921-925

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13 November 2017

6237

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Galactose metabolic genes in yeast respond to a ratio of galactose and glucose.

13 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Single step BP/LR combined Gateway reactions

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

The ortholog conjecture is untestable by the current gene ontology but is supported by RNA sequencing data

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Hierarchical modularity and the evolution of genetic interactomes across species.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Testing the ortholog conjecture with comparative functional genomic data from mammals

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Prioritizing candidate disease genes by network-based boosting of genome-wide association data.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Characterization of the proteome, diseases and evolution of the human postsynaptic density.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Mammalian microRNAs predominantly act to decrease target mRNA levels

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

The use of orthologous sequences to predict the impact of amino acid substitutions on protein function

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

The genetic landscape of a cell

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

The completion of the Mammalian Gene Collection (MGC).

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

CORUM: the comprehensive resource of mammalian protein complexes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Rescuing yeast mutants with human genes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Orthology and functional conservation in eukaryotes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

BioGRID: a general repository for interaction datasets

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Towards a proteome-scale map of the human protein–protein interaction network

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

The application of statistical physics to evolutionary biology

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Inparanoid: a comprehensive database of eukaryotic orthologs

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

MVK mutations and associated clinical features in Italian patients affected with autoinflammatory disorders and recurrent fever

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

The timing of eukaryotic evolution: does a relaxed molecular clock reconcile proteins and fossils?

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Accumulating Dobzhansky-Muller incompatibilities: reconciling theory and data

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Exploration of essential gene functions via titratable promoter alleles

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Carrier frequency of the V377I (1129G>A) MVK mutation, associated with Hyper-IgD and periodic fever syndrome, in the Netherlands

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Automatic clustering of orthologs and in-paralogs from pairwise species comparisons

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Systematic genetic analysis with ordered arrays of yeast deletion mutants

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Nonorthologous gene displacement of phosphomevalonate kinase.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

KEGG: kyoto encyclopedia of genes and genomes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

KEGG: Kyoto Encyclopedia of Genes and Genomes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Structure of 20S proteasome from yeast at 2.4 A resolution

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

The population genetics of speciation: the evolution of hybrid incompatibilities

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Functional and evolutionary implications of gene orthology.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Significant liver disease in a patient with Y116H mutation in the MVK gene.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718922

Structural and functional conservation between yeast and human 3-hydroxy-3-methylglutaryl coenzyme A reductases, the rate-limiting enzyme of sterol biosynthesis

15 August 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA0769

A Robust Toolkit for Functional Profiling of the Yeast Genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA0769

Data mining in bioinformatics using Weka

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA0769

Autoinflammatory gene mutations in Behçet's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA0769

The structure of the mammalian 20S proteasome at 2.75 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA0769

Conserved and nonconserved functions of the yeast and human TATA-binding proteins

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25999509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A probabilistic functional network of yeast genes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25999509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Diagnostics and therapeutic insights in a severe case of mevalonate kinase deficiency

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25999509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.AAA0769

1 reference

13 November 2017

1 reference

13 November 2017

1 reference

PMCID

4718922