Comparison of potential risks of lactic acidosis induction by biguanides in rats (Q43058217)

13 November 2017

Comparison of potential risks of lactic acidosis induction by biguanides in rats (English)

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13 November 2017

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Kiyoko Bando

1

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13 November 2017

Shoko Ochiai

2

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13 November 2017

Takeshi Kunimatsu

3

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13 November 2017

Jiro Deguchi

4

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13 November 2017

Juki Kimura

5

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13 November 2017

Hitoshi Funabashi

6

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13 November 2017

Takaki Seki

7

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13 November 2017

language of work or name

English

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publication date

19 May 2010

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Regulatory Toxicology and Pharmacology

13 November 2017

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13 November 2017

58

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13 November 2017

1

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13 November 2017

155-160

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Metabolism, Plasma or Serum Levels, and Elimination of Phenformin in Guinea Pigs, Rats, and Dogs

13 November 2017

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7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

Influence of phenformin and metformin on exercise induced lactataemia in patients with diabetes mellitus.

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Lactic acidosis rates in type 2 diabetes.

7 January 2021

1 reference

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The effect of metformin on glycaemic control, intermediary metabolism and blood pressure in non-insulin-dependent diabetes mellitus.

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus.

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Irreversibility of the defect in glycogen synthase activity in skeletal muscle from obese patients with NIDDM treated with diet and metformin

7 January 2021

1 reference

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Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

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1 reference

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Multiple actions of phenylethylbiguanide on respiration by rat liver mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

The dose-dependent toxic effects of phenformin in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

Metabolism of Phenformin in the Rat and Guinea-Pig

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1 reference

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Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

Comparison of gene expression changes induced by biguanides in db/db mice liver

7 January 2021

1 reference

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A risk-benefit assessment of metformin in type 2 diabetes mellitus

7 January 2021

1 reference

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The effects of metformin compared to the effects of phenformin on the lactate production and the metabolism of isolated parenchymal rat liver cell

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1 reference

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Comparison of tolbutamide and metformin in elderly diabetic patients

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Lactate levels in Asian patients with type 2 diabetes mellitus on metformin and its association with dose of metformin and renal function

7 January 2021

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Pharmacokinetic Optimisation of Oral Hypoglycaemic Therapy

7 January 2021

1 reference

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Lactic acidosis in patients with diabetes treated with metformin

7 January 2021

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Genetic polymorphism of phenformin 4-hydroxylation

7 January 2021

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Influence of oxidation polymorphism on phenformin kinetics and dynamics

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1 reference

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Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

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Metformin in patients with type 2 diabetes mellitus: reconsideration of traditional contraindications

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1 reference

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Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus

7 January 2021

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Guanidines and biguanides

7 January 2021

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Disposition of metformin (N,N-dimethylbiguanide) in man.

7 January 2021

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7 January 2021

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Incidence of lactic acidosis in metformin users

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1 reference

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Metabolic effects of metformin in non-insulin-dependent diabetes mellitus

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1 reference

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Metformin kinetics in healthy subjects and in patients with diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2010.05.005

Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin

7 January 2021

1 reference

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Metformin-associated lactic acidosis in Sweden 1977-1991

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Inhibition of hepatic gluconeogenesis by metformin. Synergism with insulin.

7 January 2021

1 reference

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Lactic acidosis in critical illness

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10.1016/J.YRTPH.2010.05.005

7 January 2021

Identifiers

DOI

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13 November 2017

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