Stability of HAMLET--a kinetically trapped alpha-lactalbumin oleic acid complex (Q43058028)

13 November 2017

Stability of HAMLET--a kinetically trapped alpha-lactalbumin oleic acid complex (English)

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13 November 2017

4

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13 November 2017

Jonas Fast

1

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13 November 2017

Ann-Kristin Mossberg

series ordinal

2

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13 November 2017

Catharina Svanborg

series ordinal

3

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13 November 2017

1 February 2005

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13 November 2017

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13 November 2017

14

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13 November 2017

2

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13 November 2017

329-340

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Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid

13 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Lipids as cofactors in protein folding: stereo-specific lipid-protein interactions are required to form HAMLET (human alpha-lactalbumin made lethal to tumor cells).

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells)

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

HAMLET interacts with histones and chromatin in tumor cell nuclei

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Extended disordered proteins: targeting function with less scaffold

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Insights into the structure and dynamics of unfolded proteins from nuclear magnetic resonance

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Natively unfolded proteins: a point where biology waits for physics

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Beta-1,4-galactosyltransferase and lactose synthase: molecular mechanical devices

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

What does it mean to be natively unfolded?

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Magnetic relaxation dispersion studies of biomolecular solutions.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Intrinsically disordered protein

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Comparison of the structural and dynamical properties of holo and apo bovine alpha-lactalbumin by NMR spectroscopy.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Prion propagation and molecular chaperones

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Crystal structures of apo- and holo-bovine alpha-lactalbumin at 2. 2-A resolution reveal an effect of calcium on inter-lobe interactions

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Conversion of alpha-lactalbumin to a protein inducing apoptosis

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Energetics of solvent and ligand-induced conformational changes in alpha-lactalbumin.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Multimeric alpha-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

MOLMOL: a program for display and analysis of macromolecular structures

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

The molten globule state of alpha-lactalbumin.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

How to measure and predict the molar absorption coefficient of a protein

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

A spring-loaded mechanism for the conformational change of influenza hemagglutinin

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Kinetics versus thermodynamics in protein folding

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Apoptosis induced by a human milk protein

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Different subdomains are most protected from hydrogen exchange in the molten globule and native states of human alpha-lactalbumin

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

‘Molten‐globule state’: a compact form of globular proteins with mobile side‐chains

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Refined structure of baboon alpha-lactalbumin at 1.7 A resolution. Comparison with C-type lysozyme

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Metal-ion binding and the molecular conformational properties of alpha lactalbumin

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Ligand-induced biphasic protein denaturation.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Energetic landscape of alpha-lytic protease optimizes longevity through kinetic stability

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Contribution of folding steps involving the individual subunits of bacterial luciferase to the assembly of the active heterodimeric enzyme.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Energetics of the alpha-lactalbumin states: a calorimetric and statistical thermodynamic study.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2253409

Equilibrium and Kinetic Studies on Folding of the Authentic and Recombinant Forms of Human α-Lactalbumin by Circular Dichroism Spectroscopy†

15 August 2018

1 reference

12 December 2020

Detection and characterization of the intermediate on the folding pathway of human alpha-lactalbumin

1 reference

12 December 2020

Alpha-Lactalbumin: compact state with fluctuating tertiary structure?

1 reference

12 December 2020

Cation binding effects on the pH, thermal and urea denaturation transitions in alpha-lactalbumin

1 reference

12 December 2020

Compact state of a protein molecule with pronounced small-scale mobility: bovine alpha-lactalbumin

1 reference

12 December 2020

Influence of Ca2+ binding on the structure and stability of bovine alpha-lactalbumin studied by circular dichroism and nuclear magnetic resonance spectra

1 reference

12 December 2020

Physical nature of the phase transition in globular proteins. Calorimetric study of human alpha-lactalbumin

1 reference

12 December 2020

Ca2+-induced alteration in the unfolding behavior of alpha-lactalbumin

1 reference

12 December 2020

Crystal structure of human α-lactalbumin at 1·7 Å resolution

1 reference

12 December 2020

Thermodynamic characterization of the partially unfolded state of Ca(2+)-loaded bovine alpha-lactalbumin: evidence that partial unfolding can precede Ca2+ release

1 reference

12 December 2020

A residue-specific NMR view of the non-cooperative unfolding of a molten globule

1 reference

12 December 2020

Cooperative thermal transitions of bovine and human apo-α-lactalbumins: evidence for a new intermediate state

1 reference

12 December 2020

INTER- AND INTRAMOLECULAR INTERACTIONS OF ALPHA-LACTALBUMIN. I. THE APPARENT HETEROGENEITY AT ACID PH

1 reference

12 December 2020

Interactions of alpha-lactalbumin with fatty acids and spin label analogs

1 reference

12 December 2020

Identifiers

DOI

10.1110/PS.04982905

1 reference

13 November 2017

1 reference

13 November 2017

PubMed publication ID

15659367

1 reference