Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy (Q43007324)

12 November 2017

Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy (English)

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12 November 2017

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Claudia Brandt

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634618&resulttype=core&format=json

15 May 2020

Maia Nozadze

2

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15 May 2020

Nina Heuchert

3

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15 May 2020

Marta Rattka

4

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15 May 2020

Wolfgang Löscher

5

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15 May 2020

language of work or name

English

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publication date

1 June 2010

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12 November 2017

Journal of Neuroscience

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15 May 2020

volume

30

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15 May 2020

issue

25

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15 May 2020

page(s)

8602-8612

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Sodium-potassium-chloride cotransport

15 May 2020

cites work

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12 December 2020

Repeated low-dose treatment of rats with pilocarpine: low mortality but high proportion of rats developing epilepsy

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12 December 2020

Expression of Na(+)-K(+)-Cl(-) cotransporter in rat brain during development and its localization in mature astrocytes

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12 December 2020

Pharmacokinetics and pharmacodynamics of intravenous bumetanide in mutant Nagase analbuminemic rats: importance of globulin binding for the pharmacodynamic effects

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12 December 2020

Postnatal maturation of Na+, K+, 2Cl- cotransporter expression and inhibitory synaptogenesis in the rat hippocampus: an immunocytochemical analysis

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12 December 2020

Rat NKCC2/NKCC1 cotransporter selectivity for loop diuretic drugs

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12 December 2020

Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy

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12 December 2020

P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats

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12 December 2020

Neuroscience. GABA becomes exciting

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12 December 2020

The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review

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12 December 2020

Cation-chloride co-transporters in neuronal communication, development and trauma

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12 December 2020

The neurobiology of antiepileptic drugs

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12 December 2020

Atipamezole, an alpha(2)-adrenoceptor antagonist, has disease modifying effects on epileptogenesis in rats

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12 December 2020

Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticus.

1 reference

12 December 2020

Epilepsy induced by extended amygdala-kindling in rats: lack of clear association between development of spontaneous seizures and neuronal damage

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12 December 2020

The multiple facets of gamma-aminobutyric acid dysfunction in epilepsy

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12 December 2020

A 5-month period of epilepsy impairs spatial memory, decreases anxiety, but spares object recognition in the lithium-pilocarpine model in adult rats

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12 December 2020

NKCC1 transporter facilitates seizures in the developing brain

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12 December 2020

Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy

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12 December 2020

Acute changes in the neuronal expression of GABA and glutamate decarboxylase isoforms in the rat piriform cortex following status epilepticus

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12 December 2020

Treatment with valproate after status epilepticus: effect on neuronal damage, epileptogenesis, and behavioral alterations in rats

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12 December 2020

Inhibition of the Na+ -K+ -2Cl- -cotransporter in choroid plexus attenuates traumatic brain injury-induced brain edema and neuronal damage.

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12 December 2020

Stereological methods reveal the robust size and stability of ectopic hilar granule cells after pilocarpine-induced status epilepticus in the adult rat

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12 December 2020

The pharmacokinetics of antiepileptic drugs in rats: consequences for maintaining effective drug levels during prolonged drug administration in rat models of epilepsy

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12 December 2020

Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats.

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12 December 2020

Bumetanide administration attenuated traumatic brain injury through IL-1 overexpression

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12 December 2020

Developmental patterns in the regulation of chloride homeostasis and GABA(A) receptor signaling by seizures

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12 December 2020

Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.

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12 December 2020

Disrupted dentate granule cell chloride regulation enhances synaptic excitability during development of temporal lobe epilepsy

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12 December 2020

AMPA receptor antagonists: potential therapeutic applications.

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12 December 2020

Glutamate is critically involved in seizure-induced overexpression of P-glycoprotein in the brain

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12 December 2020

Long-term expressional changes of Na+ -K+ -Cl- co-transporter 1 (NKCC1) and K+ -Cl- co-transporter 2 (KCC2) in CA1 region of hippocampus following lithium-pilocarpine induced status epilepticus (PISE).

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12 December 2020

Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus

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12 December 2020

Molecular and cellular basis of epileptogenesis in symptomatic epilepsy

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12 December 2020

Complex time-dependent alterations in the brain expression of different drug efflux transporter genes after status epilepticus.

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12 December 2020

Posttraumatic epilepsy: the challenge of translating discoveries in the laboratory to pathways to a cure

1 reference

12 December 2020

Bumetanide inhibits rapid kindling in neonatal rats

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12 December 2020

Cation-chloride cotransporters and neuronal function

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12 December 2020

Curing epilepsy: progress and future directions

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12 December 2020

Pursuing paradoxical proconvulsant prophylaxis for epileptogenesis

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12 December 2020

Development of epileptiform excitability in the deep entorhinal cortex after status epilepticus

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12 December 2020

A relationship between the metabolism of bumetanide and its diuretic activity in the rat

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12 December 2020

Characteristics and functions of Na-K-Cl cotransport in epithelial tissues

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12 December 2020

Modification of seizure activity by electrical stimulation. II. Motor seizure

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12 December 2020

Pharmacological properties of 3-n-butylamino-4-phenoxy-5-sulfamylbenzoic acid (Bumetanide), a new potent diuretic

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12 December 2020

Pharmacokinetics and metabolism of bumetanide in man, dog and rat (author's transl)

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12 December 2020

Comparison of anticonvulsant efficacy of valproate during prolonged treatment with one and three daily doses or continuous ("controlled release") administration in a model of generalized seizures in rats

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12 December 2020

Pharmacokinetics and pharmacodynamics of bumetanide after intravenous and oral administration to rats: absorption from various GI segments

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12 December 2020

The interplay of learning and anxiety in the elevated plus-maze

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12 December 2020

A comparative diuretic and tissue distribution study of bumetanide and furosemide in the dog.

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12 December 2020

The pharmacokinetics of bumetanide in the newborn infant

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12 December 2020

Comparison of valproate and phenobarbital treatment after status epilepticus in rats.

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12 December 2020

Ontogeny of cation-Cl- cotransporter expression in rat neocortex.

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12 December 2020

Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits

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12 December 2020

10.1523/JNEUROSCI.0633-10.2010

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634618&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6634618&resulttype=core&format=json

15 May 2020

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