Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes (Q42991206)

12 November 2017

Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes (English)

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12 November 2017

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12 November 2017

Nigel J Stevenson

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12 November 2017

Nollaig M Bourke

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12 November 2017

Liam Fanning

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12 November 2017

James A Johnston

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12 November 2017

John E Hegarty

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12 November 2017

Aideen Long

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12 November 2017

Cliona O'Farrelly

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12 November 2017

language of work or name

English

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publication date

12 April 2013

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12 November 2017

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587

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12 November 2017

1571-1578

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10

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The prevalence of hepatitis C virus infection in the United States, 1999 through 2002

12 November 2017

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

T cell responses in hepatitis C: the good, the bad and the unconventional

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

The affect of chronic hepatitis C infection on dendritic cell function: a summary of the experimental evidence.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Intracellular innate immune cascades and interferon defenses that control hepatitis C virus

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Interferon-alpha activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Viruses and the 26S proteasome: hacking into destruction

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Weapons of STAT destruction. Interferon evasion by paramyxovirus V protein

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Ribavirin enhances IFN-α signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Hepatitis C virus expression suppresses interferon signaling by degrading STAT1

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Experimental models for hepatitis C viral infection

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Hepatitis C infection of B lymphocytes: more tools to address pending questions.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Activation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular Transformation

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Hepatitis C virus NS5A mediated STAT3 activation requires co-operation of Jak1 kinase

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in Hepatitis C virus replicon

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Deficient Stat3 DNA-binding is associated with high Pias3 expression and a positive anti-apoptotic balance in human end-stage alcoholic and hepatitis C cirrhosis

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

HCV structural proteins interfere with interferon-alpha Jak/STAT signalling pathway

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Role of Stat3 in suppressing anti-tumor immunity

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Role of signal transducer and activator of transcription 3 in liver fibrosis progression in chronic hepatitis C-infected patients

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.03.041

10.1016/J.FEBSLET.2013.03.041

21 January 2018

Identifiers

DOI

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12 November 2017

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