Zinc, insulin, and the liver: a ménage à trois (Q42966504)

11 November 2017

Zinc, insulin, and the liver: a ménage à trois (English)

1 reference

11 November 2017

Melkam Kebede

2

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author name string

Thomas V O'Halloran

series ordinal

1

1 reference

11 November 2017

Steven J Philips

series ordinal

3

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11 November 2017

Alan D Attie

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4

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11 November 2017

language of work or name

English

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publication date

24 September 2013

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Journal of Clinical Investigation

11 November 2017

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11 November 2017

123

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11 November 2017

4136-4139

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11 November 2017

10

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The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

11 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Tolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cells

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

How insulin engages its primary binding site on the insulin receptor

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

The physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic background

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Effects of high-fat diet feeding on Znt8-null mice: differences between β-cell and global knockout of Znt8

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Fasting insulin reflects heterogeneous physiological processes: role of insulin clearance

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

A genome-wide association study identifies novel risk loci for type 2 diabetes

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Two SUR1-specific histidine residues mandatory for zinc-induced activation of the rat KATP channel

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Imaging of Zn2+ release from pancreatic beta-cells at the level of single exocytotic events.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Molecular evolution of rodent insulins

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784553

16 August 2018

Identifiers

DOI

10.1172/JCI72325

1 reference

release_puvbylwitffqvnqkqo3ejq3f2i

11 November 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/puvbylwitffqvnqkqo3ejq3f2i

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

11 November 2017

1 reference