Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies. (Q42872955)

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scientific article published on January 2008

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English	Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies.	scientific article published on January 2008

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scholarly article

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8 January 2020

Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies (English)

1 reference

Europe PubMed Central

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8 January 2020

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Didier Stainier

2

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8 January 2020

1

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Silvia Curado

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8 January 2020

author name string

Ryan M Anderson

3

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8 January 2020

publication date

1 January 2008

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8 January 2020

Nature Protocols

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8 January 2020

3

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8 January 2020

948-954

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8 January 2020

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8 January 2020

https://scigraph.springernature.com/pub.10.1038/nprot.2008.58

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Ablation of tumor-derived stem cells transplanted to the central nervous system by genetic modification of embryonic stem cells with a suicide gene

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Rat adenocarcinoma cell line infected with an adenovirus carrying a novel herpes-simplex virus-thymidine kinase suicide gene construct dies by apoptosis upon treatment with ganciclovir

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Targeted cell-ablation in Xenopus embryos using the conditional, toxic viral protein M2(H37A).

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Liver growth in the embryo and during liver regeneration in zebrafish requires the cell cycle regulator, uhrf1

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Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase

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Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter

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27 May 2018

Nitroreductase: a prodrug-activating enzyme for cancer gene therapy.

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27 May 2018

Larval melanocyte regeneration following laser ablation in zebrafish

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27 May 2018

A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish

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Neomycin-induced hair cell death and rapid regeneration in the lateral line of zebrafish (Danio rerio).

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27 May 2018

In vivo studies of liver-type fatty acid binding protein (L-FABP) gene expression in liver of transgenic zebrafish (Danio rerio).

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27 May 2018

Heart regeneration in zebrafish

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27 May 2018

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

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27 May 2018

Conditional ablation of neurones in transgenic mice.

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27 May 2018

Approaches to gene-directed enzyme prodrug therapy (GDEPT).

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27 May 2018

The bystander effect of the nitroreductase/CB1954 enzyme/prodrug system is due to a cell-permeable metabolite

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27 May 2018

Increased expression of specific recognition molecules by retinal ganglion cells and by optic pathway glia accompanies the successful regeneration of retinal axons in adult zebrafish.

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27 May 2018

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.

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27 May 2018

Temperature-sensitive mutations that cause stage-specific defects in Zebrafish fin regeneration.

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27 May 2018

Nitroimidazole drugs--action and resistance mechanisms. II. Mechanisms of resistance

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27 May 2018

The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)--I. Purification and properties of a nitroreductase enzyme from Escherichia coli--a potential enzyme for antibody-directed enzyme prodrug therapy (ADEPT).

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27 May 2018

Antitrichomonad action, mutagenicity, and reduction of metronidazole and other nitroimidazoles

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Conditional targeted cell ablation in zebrafish: a new tool for regeneration studies

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Absorption, tissue concentration, and organ distribution of cefazolin

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7 January 2021

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10.1038/NPROT.2008.58

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536643%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536643%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536643%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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