The activity of the thiazide-sensitive Na(+)-Cl(-) cotransporter is regulated by protein phosphatase PP4. (Q42852253)

8 November 2017

The activity of the thiazide-sensitive Na(+)-Cl(-) cotransporter is regulated by protein phosphatase PP4. (English)

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8 November 2017

2

Annie Mercier Zuber

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8 November 2017

Mark Glover

1

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8 November 2017

Nikki Figg

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3

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8 November 2017

Kevin M O'Shaughnessy

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4

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8 November 2017

language of work or name

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1 October 2010

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Canadian Journal of Physiology and Pharmacology

8 November 2017

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8 November 2017

88

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10

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8 November 2017

986-995

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WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells

8 November 2017

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WNK kinases and the control of blood pressure

21 January 2018

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A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1.

21 January 2018

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WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway

21 January 2018

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SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

21 January 2018

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Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.

21 January 2018

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WNK4 kinase is a negative regulator of K+-Cl- cotransporters.

21 January 2018

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Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein.

21 January 2018

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Renal and brain isoforms of WNK3 have opposite effects on NCCT expression

21 January 2018

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A new kindred with pseudohypoaldosteronism type II and a novel mutation (564D>H) in the acidic motif of the WNK4 gene

21 January 2018

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Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved.

21 January 2018

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Genomic structure of the mouse PP4 gene: a developmentally regulated protein phosphatase

21 January 2018

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WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia

21 January 2018

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WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.

21 January 2018

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Molecular physiology of the WNK kinases.

21 January 2018

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WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

21 January 2018

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The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

21 January 2018

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Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases

21 January 2018

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Role of the WNK-activated SPAK kinase in regulating blood pressure

21 January 2018

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Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

21 January 2018

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WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis

21 January 2018

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A novel missense mutation in AE1 causing autosomal dominant distal renal tubular acidosis retains normal transport function but is mistargeted in polarized epithelial cells

21 January 2018

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Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway

21 January 2018

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Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter

21 January 2018

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Molecular cloning and characterization of Atp6n1b: a novel fourth murine vacuolar H+-ATPase a-subunit gene

21 January 2018

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WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction

21 January 2018

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Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

21 January 2018

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Structural insights into the recognition of substrates and activators by the OSR1 kinase

21 January 2018

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The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

21 January 2018

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Guidelines for management of hypertension: report of the fourth working party of the British Hypertension Society, 2004-BHS IV.

21 January 2018

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Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

21 January 2018

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The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y10-080

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8 November 2017

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