Analysis of genetic events that modulate the oncogenic and growth suppressive activities of the PAX3-FKHR fusion oncoprotein (Q42831049)

8 November 2017

Analysis of genetic events that modulate the oncogenic and growth suppressive activities of the PAX3-FKHR fusion oncoprotein (English)

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8 November 2017

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4

Frederic G Barr

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8 November 2017

Shujuan J Xia

1

1 reference

PubMed ID

17297479

8 November 2017

Prerna Rajput

series ordinal

2

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PubMed ID

17297479

8 November 2017

Donna M Strzelecki

series ordinal

3

1 reference

8 November 2017

12 February 2007

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8 November 2017

Laboratory Investigation

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8 November 2017

87

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8 November 2017

4

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8 November 2017

318-325

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https://scigraph.springernature.com/pub.10.1038/labinvest.3700521

8 November 2017

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cites work

Molecular pathogenesis of rhabdomyosarcoma

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Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma

21 January 2018

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Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma

21 January 2018

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Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

Co-expression of alternatively spliced forms of PAX3, PAX7, PAX3-FKHR and PAX7-FKHR with distinct DNA binding and transactivation properties in rhabdomyosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

Analysis of the transforming and growth suppressive activities of the PAX3-FKHR oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

Mutations in PAX3 that cause Waardenburg syndrome type I: ten new mutations and review of the literature

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

A consensus polymerase chain reaction-oligonucleotide hybridization approach for the detection of chromosomal translocations in pediatric bone and soft tissue sarcomas

21 January 2018

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7 January 2021

Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma, whereas amplification predominates in embryonal with anaplasia and alveolar subtypes

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

7 January 2021

A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcoma

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7 January 2021

Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

7 January 2021

Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

7 January 2021

The paired-domain regulates DNA binding by the homeodomain within the intact Pax-3 protein

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700521

7 January 2021

10.1038/LABINVEST.3700521

Identifiers

DOI

1 reference

8 November 2017

1 reference

PubMed ID

17297479