A conserved 3'-untranslated element mediates growth regulation of DNA methyltransferase 1 and inhibits its transforming activity (Q42829298)

8 November 2017

A conserved 3'-untranslated element mediates growth regulation of DNA methyltransferase 1 and inhibits its transforming activity (English)

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8 November 2017

Detich N

1

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8 November 2017

Ramchandani S

series ordinal

2

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8 November 2017

Szyf M

series ordinal

3

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8 November 2017

language of work or name

English

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publication date

2 May 2001

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Journal of Biological Chemistry

8 November 2017

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8 November 2017

276

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8 November 2017

27

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8 November 2017

24881-24890

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CpG methylation, chromatin structure and gene silencing-a three-way connection

8 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

DNA Methylation and Gene Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

DNA methylation pattern is determined by the intracellular level of the methylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

The DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Regulation of the DNA methylation machinery and its role in cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Concurrent replication and methylation at mammalian origins of replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Inhibition of DNA methyltransferase inhibits DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Regulation of DNA methylation by the Ras signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

DNA methyltransferase is a downstream effector of cellular transformation triggered by simian virus 40 large T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

A beta vasoactivity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Regulation of mRNA stability in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Regulation of the stability of heat-stable antigen mRNA by interplay between two novel cis elements in the 3' untranslated region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

p21(waf1) mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5' element and c-fos 3' sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

c-jun N-terminal kinase is involved in AUUUA-mediated interleukin-3 mRNA turnover in mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Growth-condition-dependent regulation of insulin-like growth factor II mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Developmental regulation of RNA transcript destabilization by A + U-rich elements is AUF1-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Hormonal regulation of mRNA stability and RNA-protein interactions in the pituitary

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

A simplified system for generating recombinant adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

cis modification of the steroid 21-hydroxylase gene prevents its expression in the Y1 mouse adrenocortical tumor cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Differential DNA replication origin activities in human normal skin fibroblast and HeLa cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

In differentiating mouse myoblasts DNA methyltransferase is posttranscriptionally and posttranslationally regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Regulation of the mRNA-binding protein AUF1 by activation of the beta-adrenergic receptor signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Evolutionary conservation of the AU-rich 3' untranslated region of messenger RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Highly conserved RNA sequences that are sensors of environmental stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Analysis of the AU-rich elements in the 3'-untranslated region of beta 2-adrenergic receptor mRNA by mutagenesis and identification of the homologous AU-rich region from different species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Identification of a large region of secondary structure in the 3'-untranslated region of chicken elastin mRNA with implications for the regulation of mRNA stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Adhesion-dependent regulation of an A+U-rich element-binding activity associated with AUF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

One or more labile proteins regulate the stability of chimeric mRNAs containing the 3'-untranslated region of cholesterol-7alpha -hydroxylase mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103056200

21 January 2018

Identifiers

DOI

10.1074/JBC.M103056200

1 reference

8 November 2017

1 reference