P27 expression is regulated by separate signaling pathways, downstream of Ras, in each cell cycle phase (Q42824704)

8 November 2017

P27 expression is regulated by separate signaling pathways, downstream of Ras, in each cell cycle phase (English)

1 reference

8 November 2017

Gaurisankar Sa

1

1 reference

PubMed ID

15475007

8 November 2017

Dennis W Stacey

series ordinal

2

1 reference

PubMed ID

15475007

8 November 2017

language of work or name

English

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publication date

1 November 2004

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Experimental Cell Research

8 November 2017

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8 November 2017

300

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8 November 2017

2

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8 November 2017

427-439

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CDK inhibitors: positive and negative regulators of G1-phase progression

8 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

p21Waf1 inhibits the activity of cyclin dependent kinase 2 by preventing its activating phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Growth-factor-dependent mitogenesis requires two distinct phases of signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

MAP kinase cascade is required for p27 downregulation and S phase entry in fibroblasts and epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

G1 phase arrest by the phosphatidylinositol 3-kinase inhibitor LY 294002 is correlated to up-regulation of p27Kip1 and inhibition of G1 CDKs in choroidal melanoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Cyclin E-CDK2 is a regulator of p27Kip1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Proliferation of cancer cells despite CDK2 inhibition.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Cdk2 knockout mice are viable

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Cyclin D1 production in cycling cells depends on ras in a cell-cycle-specific manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

The Raf/MEK/ERK pathway: new concepts of activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Blockade of the extracellular signal-regulated kinase pathway induces marked G1 cell cycle arrest and apoptosis in tumor cells in which the pathway is constitutively activated: up-regulation of p27(Kip1)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Ras-dependent cell cycle commitment during G2 phase

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Dual control of cell growth by somatomedins and platelet-derived growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Cellular ras and cyclin D1 are required during different cell cycle periods in cycling NIH 3T3 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.07.032

10.1016/J.YEXCR.2004.07.032

7 January 2021

Identifiers

DOI

1 reference

8 November 2017

1 reference

PubMed ID

15475007